Expression of galectin-1 in malignant tumors

Galectin-1 is a 14 kDa lectin expressed ubiquitously in mammalian organism. Since its discovery, the lectin was shown to participate in many cellular processes. Involvement in some of them like induction of apoptosis of activated T cells, mediation of cell adhesion and participation in angiogenesi...

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Published in:Experimental Oncology
Date:2009
Main Authors: Demydenko, D., Berest, I.
Format: Article
Language:English
Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2009
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Online Access:https://nasplib.isofts.kiev.ua/handle/123456789/135729
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Journal Title:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Cite this:Expression of galectin-1 in malignant tumors / D. Demydenko, I. Berest // Experimental Oncology. — 2009. — Т. 31, № 2. — С. 74-79. — Бібліогр.: 74 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine
id nasplib_isofts_kiev_ua-123456789-135729
record_format dspace
spelling Demydenko, D.
Berest, I.
2018-06-15T14:21:59Z
2018-06-15T14:21:59Z
2009
Expression of galectin-1 in malignant tumors / D. Demydenko, I. Berest // Experimental Oncology. — 2009. — Т. 31, № 2. — С. 74-79. — Бібліогр.: 74 назв. — англ.
1812-9269
https://nasplib.isofts.kiev.ua/handle/123456789/135729
Galectin-1 is a 14 kDa lectin expressed ubiquitously in mammalian organism. Since its discovery, the lectin was shown to participate in many cellular processes. Involvement in some of them like induction of apoptosis of activated T cells, mediation of cell adhesion and participation in angiogenesis suggest that galectin-1 could be utilized by malignant tumors. Indeed expression of galectin-1 is upregulated in tumors of different origin. Many examples point to its important role in a process of cancer metastasis. This review summarizes the data available to date on galectin-1 expression in human malignancies.
en
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
Experimental Oncology
Reviews
Expression of galectin-1 in malignant tumors
Article
published earlier
institution Digital Library of Periodicals of National Academy of Sciences of Ukraine
collection DSpace DC
title Expression of galectin-1 in malignant tumors
spellingShingle Expression of galectin-1 in malignant tumors
Demydenko, D.
Berest, I.
Reviews
title_short Expression of galectin-1 in malignant tumors
title_full Expression of galectin-1 in malignant tumors
title_fullStr Expression of galectin-1 in malignant tumors
title_full_unstemmed Expression of galectin-1 in malignant tumors
title_sort expression of galectin-1 in malignant tumors
author Demydenko, D.
Berest, I.
author_facet Demydenko, D.
Berest, I.
topic Reviews
topic_facet Reviews
publishDate 2009
language English
container_title Experimental Oncology
publisher Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
format Article
description Galectin-1 is a 14 kDa lectin expressed ubiquitously in mammalian organism. Since its discovery, the lectin was shown to participate in many cellular processes. Involvement in some of them like induction of apoptosis of activated T cells, mediation of cell adhesion and participation in angiogenesis suggest that galectin-1 could be utilized by malignant tumors. Indeed expression of galectin-1 is upregulated in tumors of different origin. Many examples point to its important role in a process of cancer metastasis. This review summarizes the data available to date on galectin-1 expression in human malignancies.
issn 1812-9269
url https://nasplib.isofts.kiev.ua/handle/123456789/135729
citation_txt Expression of galectin-1 in malignant tumors / D. Demydenko, I. Berest // Experimental Oncology. — 2009. — Т. 31, № 2. — С. 74-79. — Бібліогр.: 74 назв. — англ.
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