Ribonucleases. possible new approach in cancer therapy
In the review, the use of the ribonucleases for cancer therapy is discussed. Using of epigenetic mechanisms of regulation — blocking
 protein synthesis without affecting the DNA structure — is a promising direction in the therapy. The ribonucleases isolated from different
 sources, d...
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| Published in: | Experimental Oncology |
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| Date: | 2016 |
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| Format: | Article |
| Language: | English |
| Published: |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2016
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| Online Access: | https://nasplib.isofts.kiev.ua/handle/123456789/136133 |
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| Journal Title: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Cite this: | Ribonucleases. possible new approach in cancer therapy / V.O. Shlyakhovenko // Experimental Oncology. — 2016 — Т. 38, № 1. — С. 2–8. — Бібліогр.: 47 назв. — англ. |
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Digital Library of Periodicals of National Academy of Sciences of Ukraine| _version_ | 1862669045912829952 |
|---|---|
| author | Shlyakhovenko, V.O. |
| author_facet | Shlyakhovenko, V.O. |
| citation_txt | Ribonucleases. possible new approach in cancer therapy / V.O. Shlyakhovenko // Experimental Oncology. — 2016 — Т. 38, № 1. — С. 2–8. — Бібліогр.: 47 назв. — англ. |
| collection | DSpace DC |
| container_title | Experimental Oncology |
| description | In the review, the use of the ribonucleases for cancer therapy is discussed. Using of epigenetic mechanisms of regulation — blocking
protein synthesis without affecting the DNA structure — is a promising direction in the therapy. The ribonucleases isolated from different
sources, despite of similar mechanism of enzymatic reactions, have different biological effects. The use of enzymes isolated from new
sources, particularly from plants and fungi, shows promising results. In this article we discuss the new approach for the use of enzymes
resistant to inhibitors and ribozymes, that is aimed at the destruction of the oncogene specific mRNA and the induction of apoptosis.
|
| first_indexed | 2025-12-07T15:27:22Z |
| format | Article |
| fulltext | |
| id | nasplib_isofts_kiev_ua-123456789-136133 |
| institution | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| issn | 1812-9269 |
| language | English |
| last_indexed | 2025-12-07T15:27:22Z |
| publishDate | 2016 |
| publisher | Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| record_format | dspace |
| spelling | Shlyakhovenko, V.O. 2018-06-15T21:37:47Z 2018-06-15T21:37:47Z 2016 Ribonucleases. possible new approach in cancer therapy / V.O. Shlyakhovenko // Experimental Oncology. — 2016 — Т. 38, № 1. — С. 2–8. — Бібліогр.: 47 назв. — англ. 1812-9269 https://nasplib.isofts.kiev.ua/handle/123456789/136133 In the review, the use of the ribonucleases for cancer therapy is discussed. Using of epigenetic mechanisms of regulation — blocking
 protein synthesis without affecting the DNA structure — is a promising direction in the therapy. The ribonucleases isolated from different
 sources, despite of similar mechanism of enzymatic reactions, have different biological effects. The use of enzymes isolated from new
 sources, particularly from plants and fungi, shows promising results. In this article we discuss the new approach for the use of enzymes
 resistant to inhibitors and ribozymes, that is aimed at the destruction of the oncogene specific mRNA and the induction of apoptosis. en Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України Experimental Oncology Reviews Ribonucleases. possible new approach in cancer therapy Article published earlier |
| spellingShingle | Ribonucleases. possible new approach in cancer therapy Shlyakhovenko, V.O. Reviews |
| title | Ribonucleases. possible new approach in cancer therapy |
| title_full | Ribonucleases. possible new approach in cancer therapy |
| title_fullStr | Ribonucleases. possible new approach in cancer therapy |
| title_full_unstemmed | Ribonucleases. possible new approach in cancer therapy |
| title_short | Ribonucleases. possible new approach in cancer therapy |
| title_sort | ribonucleases. possible new approach in cancer therapy |
| topic | Reviews |
| topic_facet | Reviews |
| url | https://nasplib.isofts.kiev.ua/handle/123456789/136133 |
| work_keys_str_mv | AT shlyakhovenkovo ribonucleasespossiblenewapproachincancertherapy |