Adsorption of ceftriaxon by biogenic hydroxyapatite with magnetic additions

The possibility of using nanoporous composite system based on biogenic hydroxyapatite (BHA), which alloyed by ferromagnetic additives due to using two methods of physicochemical mixing, as a carrier of drugs for orthopedics and traumatology was shown. It was found that the sample obtained by precipi...

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Published in:Functional Materials
Date:2017
Main Authors: Otychenko, O.M., Babutina, T.Ye., Kuda, O.A., Budylina, O.M., Protsenko, L.S., Koval, O.Yu., Uvarova, I.V.
Format: Article
Language:English
Published: НТК «Інститут монокристалів» НАН України 2017
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Online Access:https://nasplib.isofts.kiev.ua/handle/123456789/136858
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Journal Title:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Cite this:Adsorption of ceftriaxon by biogenic hydroxyapatite with magnetic additions / O.M. Otychenko, T.Ye. Babutina, O.A. Kuda, O.M. Budylina, L.S. Protsenko, O.Yu. Koval, I.V. Uvarova // Functional Materials. — 2017. — Т. 24, № 4. — С. 577-583. — Бібліогр.: 30 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine
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Summary:The possibility of using nanoporous composite system based on biogenic hydroxyapatite (BHA), which alloyed by ferromagnetic additives due to using two methods of physicochemical mixing, as a carrier of drugs for orthopedics and traumatology was shown. It was found that the sample obtained by precipitation previously prepared iron oxalate on the surface of BHA microspheres has a greater adsorption activity than the sample obtained by including BHA directly in the process of obtaining iron oxalate (300 and 175 mg/g respectively). However, due to the difference in porosity, they are capable to hold a different amount of the injected antibiotic mass: 6 mass.% - for material obtained by physico-mechanical method and 10 mass.% - for the sample obtained by chemical method.
ISSN:1027-5495