Poly(lactic acid) scaffolds modified by gelatin for the controlled release of tetrandrine in vitro
To mimic natural extracellular matrix architecture, tetrandrine-loaded poly(L-lactic acid) scaffolds modified by gelatin were prepared via phase separation, solvent replacement and freeze-drying. The purpose of this work was to combine the biological effects of tetrandrine and the advantages of poly...
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| Published in: | Functional Materials |
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| Date: | 2017 |
| Main Author: | |
| Format: | Article |
| Language: | English |
| Published: |
НТК «Інститут монокристалів» НАН України
2017
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| Online Access: | https://nasplib.isofts.kiev.ua/handle/123456789/136891 |
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| Journal Title: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Cite this: | Poly(lactic acid) scaffolds modified by gelatin for the controlled release of tetrandrine in vitro / Zhang Ye // Functional Materials. — 2017. — Т. 24, № 4. — С. 660-666. — Бібліогр.: 34 назв. — англ. |
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Digital Library of Periodicals of National Academy of Sciences of Ukraine| _version_ | 1862660451975823360 |
|---|---|
| author | Zhang Ye |
| author_facet | Zhang Ye |
| citation_txt | Poly(lactic acid) scaffolds modified by gelatin for the controlled release of tetrandrine in vitro / Zhang Ye // Functional Materials. — 2017. — Т. 24, № 4. — С. 660-666. — Бібліогр.: 34 назв. — англ. |
| collection | DSpace DC |
| container_title | Functional Materials |
| description | To mimic natural extracellular matrix architecture, tetrandrine-loaded poly(L-lactic acid) scaffolds modified by gelatin were prepared via phase separation, solvent replacement and freeze-drying. The purpose of this work was to combine the biological effects of tetrandrine and the advantages of poly(L-lactic acid) scaffolds which was modified by gelatin to enhancing the mass transfer features of controlled release systems. Tetrandrine contained in the scaffolds was confirmed by X-ray photoelectron spectroscopy (XPS) and Fourier-transform infrared (FT-IR) spectroscopy. Tetrandrine did not change the morphous, crystallinity and thermodynamics of the scaffolds which demonstrated by differential scanning calorimetry (DSC), scanning electron microscopy (SEM) and X-ray powder diffractometry (XRD). The results of this study showed a sustained release with 79.15% for 188 days in vitro.
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| first_indexed | 2025-12-02T10:56:05Z |
| format | Article |
| fulltext | |
| id | nasplib_isofts_kiev_ua-123456789-136891 |
| institution | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| issn | 1027-5495 |
| language | English |
| last_indexed | 2025-12-02T10:56:05Z |
| publishDate | 2017 |
| publisher | НТК «Інститут монокристалів» НАН України |
| record_format | dspace |
| spelling | Zhang Ye 2018-06-16T17:23:41Z 2018-06-16T17:23:41Z 2017 Poly(lactic acid) scaffolds modified by gelatin for the controlled release of tetrandrine in vitro / Zhang Ye // Functional Materials. — 2017. — Т. 24, № 4. — С. 660-666. — Бібліогр.: 34 назв. — англ. 1027-5495 DOI: https://doi.org/10.15407/fm24.04.660 https://nasplib.isofts.kiev.ua/handle/123456789/136891 To mimic natural extracellular matrix architecture, tetrandrine-loaded poly(L-lactic acid) scaffolds modified by gelatin were prepared via phase separation, solvent replacement and freeze-drying. The purpose of this work was to combine the biological effects of tetrandrine and the advantages of poly(L-lactic acid) scaffolds which was modified by gelatin to enhancing the mass transfer features of controlled release systems. Tetrandrine contained in the scaffolds was confirmed by X-ray photoelectron spectroscopy (XPS) and Fourier-transform infrared (FT-IR) spectroscopy. Tetrandrine did not change the morphous, crystallinity and thermodynamics of the scaffolds which demonstrated by differential scanning calorimetry (DSC), scanning electron microscopy (SEM) and X-ray powder diffractometry (XRD). The results of this study showed a sustained release with 79.15% for 188 days in vitro. en НТК «Інститут монокристалів» НАН України Functional Materials Technology Poly(lactic acid) scaffolds modified by gelatin for the controlled release of tetrandrine in vitro Article published earlier |
| spellingShingle | Poly(lactic acid) scaffolds modified by gelatin for the controlled release of tetrandrine in vitro Zhang Ye Technology |
| title | Poly(lactic acid) scaffolds modified by gelatin for the controlled release of tetrandrine in vitro |
| title_full | Poly(lactic acid) scaffolds modified by gelatin for the controlled release of tetrandrine in vitro |
| title_fullStr | Poly(lactic acid) scaffolds modified by gelatin for the controlled release of tetrandrine in vitro |
| title_full_unstemmed | Poly(lactic acid) scaffolds modified by gelatin for the controlled release of tetrandrine in vitro |
| title_short | Poly(lactic acid) scaffolds modified by gelatin for the controlled release of tetrandrine in vitro |
| title_sort | poly(lactic acid) scaffolds modified by gelatin for the controlled release of tetrandrine in vitro |
| topic | Technology |
| topic_facet | Technology |
| url | https://nasplib.isofts.kiev.ua/handle/123456789/136891 |
| work_keys_str_mv | AT zhangye polylacticacidscaffoldsmodifiedbygelatinforthecontrolledreleaseoftetrandrineinvitro |