Expression of clusterin, XIAP and survivin, and their changes by camptothecin (CPT) treatment in CPT resistant PC-3 and CPT-sensitive LNCaP cells

• Published in: Experimental Oncology
• Date: 2006
• Main Authors: Mizutani, K., Matsumoto, K., Hasegawa, N., Deguchi, T., Nozawa, Y.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2006
• Subjects: Original contributions
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/137572
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Expression of clusterin, XIAP and survivin, and their changes by camptothecin (CPT) treatment in CPT resistant PC-3 and CPT-sensitive LNCaP cells / K. Mizutani, K. Matsumoto, N. Hasegawa, T. Deguchi, Y. Nozawa // Experimental Oncology. — 2006. — Т. 28, № 3. — С. 209-215. — Бібліогр.: 26 назв. — англ.

Aim: Clusterin and IAPs (inhibitor of apoptosis proteins), such as survivin and XIAP, are known to be related to chemo-resistance in several cancer cells. In the current study, we investigated their expression levels in human prostate cancer cell lines, LNCaP and PC-3 which are sensitive and resista...