Involvement of human beta-defensin-2 in intracellular signaling: in vitro study

• Published in: Experimental Oncology
• Date: 2006
• Main Authors: Lytvyn, D., Zhuravel, E., Markeeva, N.V., Soldatkina, M., Dudchenko, T., Pogrebnoy, P.V.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2006
• Subjects: Original contributions
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/137576
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Involvement of human beta-defensin-2 in intracellular signaling: in vitro study / D. Lytvyn, E. Zhuravel, N.V. Markeeva, M. Soldatkina, T. Dudchenko, P.V. Pogrebnoy // Experimental Oncology. — 2006. — Т. 28, № 3. — С. 198-202. — Бібліогр.: 25 назв. — англ.

Aim: To analyze involvement of human beta-defensin-2 (hBD-2) in intracellular signaling in vitro. Materials and Methods: A431cells were cultured in the presence of 1 µg/ml of recombinant hBD-2 and/or 10 ng/ml EGF. For evaluation of expression of mRNAs for p70S6 kinase, isoforms alpha and beta, RT-PC...