Diagnostic challenges with intraoral myeloid sarcoma: report of two cases & review of world literature
Background: Myeloid sarcomas (MS) are rare extramedullary tumors composed of blasts of myeloid lineage that either precede, follow or present concomitantly with acute myeloid leukaemia (AML) or myeloproliferative neoplasms. The diagnosis of MS is especially challenging in patients without an anteced...
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| Veröffentlicht in: | Experimental Oncology |
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| Datum: | 2017 |
| Format: | Artikel |
| Sprache: | English |
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Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2017
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| Zitieren: | Diagnostic challenges with intraoral myeloid sarcoma: report of two cases & review of world literature / P. Kumar, H. Singh, N. Khurana, A.B. Urs, J. Augustine, R. Tomar // Experimental Oncology. — 2017 — Т. 39, № 1. — С. 78-85. — Бібліогр.: 64 назв. — англ. |
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2018-06-17T13:54:26Z 2018-06-17T13:54:26Z 2017 Diagnostic challenges with intraoral myeloid sarcoma: report of two cases & review of world literature / P. Kumar, H. Singh, N. Khurana, A.B. Urs, J. Augustine, R. Tomar // Experimental Oncology. — 2017 — Т. 39, № 1. — С. 78-85. — Бібліогр.: 64 назв. — англ. 1812-9269 https://nasplib.isofts.kiev.ua/handle/123456789/137601 Background: Myeloid sarcomas (MS) are rare extramedullary tumors composed of blasts of myeloid lineage that either precede, follow or present concomitantly with acute myeloid leukaemia (AML) or myeloproliferative neoplasms. The diagnosis of MS is especially challenging in patients without an antecedent history of leukemia. Methods: We present 2 cases of intraoral MS that presented as de novo lesions. A detailed review of cases of intraoral MS that either preceded or presented along with leukemia has been done with emphasis on diagnostic criteria used. Results: Two male patients aged 28 and 5 years presented with MS with one patient presenting with concomitant AML. A combination of morphological and immunohistochemical methods was used for diagnosis. A thorough review of world literature revealed 44 cases of intraoral MS that presented as de novo lesions. Conclusion: Intraoral MS is a rare tumor with poor prognosis. It may be diagnostically challenging due to its protean clinical manifestations and histological overlap with other tumors. en Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України Experimental Oncology Case report Diagnostic challenges with intraoral myeloid sarcoma: report of two cases & review of world literature Article published earlier |
| institution |
Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| collection |
DSpace DC |
| title |
Diagnostic challenges with intraoral myeloid sarcoma: report of two cases & review of world literature |
| spellingShingle |
Diagnostic challenges with intraoral myeloid sarcoma: report of two cases & review of world literature Case report |
| title_short |
Diagnostic challenges with intraoral myeloid sarcoma: report of two cases & review of world literature |
| title_full |
Diagnostic challenges with intraoral myeloid sarcoma: report of two cases & review of world literature |
| title_fullStr |
Diagnostic challenges with intraoral myeloid sarcoma: report of two cases & review of world literature |
| title_full_unstemmed |
Diagnostic challenges with intraoral myeloid sarcoma: report of two cases & review of world literature |
| title_sort |
diagnostic challenges with intraoral myeloid sarcoma: report of two cases & review of world literature |
| topic |
Case report |
| topic_facet |
Case report |
| publishDate |
2017 |
| language |
English |
| container_title |
Experimental Oncology |
| publisher |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| format |
Article |
| description |
Background: Myeloid sarcomas (MS) are rare extramedullary tumors composed of blasts of myeloid lineage that either precede, follow or present concomitantly with acute myeloid leukaemia (AML) or myeloproliferative neoplasms. The diagnosis of MS is especially challenging in patients without an antecedent history of leukemia. Methods: We present 2 cases of intraoral MS that presented as de novo lesions. A detailed review of cases of intraoral MS that either preceded or presented along with leukemia has been done with emphasis on diagnostic criteria used. Results: Two male patients aged 28 and 5 years presented with MS with one patient presenting with concomitant AML. A combination of morphological and immunohistochemical methods was used for diagnosis. A thorough review of world literature revealed 44 cases of intraoral MS that presented as de novo lesions. Conclusion: Intraoral MS is a rare tumor with poor prognosis. It may be diagnostically challenging due to its protean clinical manifestations and histological overlap with other tumors.
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| issn |
1812-9269 |
| url |
https://nasplib.isofts.kiev.ua/handle/123456789/137601 |
| citation_txt |
Diagnostic challenges with intraoral myeloid sarcoma: report of two cases & review of world literature / P. Kumar, H. Singh, N. Khurana, A.B. Urs, J. Augustine, R. Tomar // Experimental Oncology. — 2017 — Т. 39, № 1. — С. 78-85. — Бібліогр.: 64 назв. — англ. |
| first_indexed |
2025-12-07T18:06:31Z |
| last_indexed |
2025-12-07T18:06:31Z |
| _version_ |
1850873784747163648 |