Circulating tumor cells in breast cancer: functional heterogeneity, pathogenetic and clinical aspects

• Published in: Experimental Oncology
• Date: 2017
• Main Authors: Cherdyntseva, N.V., Litviakov, N.V., Denisov, E.V., Gervas, P.A., Cherdyntsev, E.S.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2017
• Subjects: Reviews
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/137604
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Circulating tumor cells in breast cancer: functional heterogeneity, pathogenetic and clinical aspects / N.V. Cherdyntseva, N.V. Litviakov, E.V. Denisov, P.A. Gervas, E.S. Cherdyntsev // Experimental Oncology. — 2017 — Т. 39, № 1. — С. 2-11. — Бібліогр.: 84 назв. — англ.

Each patient has a unique history of cancer ecosystem development, resulting in intratumor heterogeneity. In order to effectively kill the tumor cells by chemotherapy, dynamic monitoring of driver molecular alterations is necessary to detect the markers for acquired drug resistance and find the new...