Aberrant promoter hypermethylation of selected apoptotic genes in childhood acute lymphoblastic leukemia among north indian population

• Published in: Experimental Oncology
• Date: 2017
• Main Authors: Nikbakht, M., Jha, A.K., Malekzadeh, K., Askari, M., Mohammadi, S., Marwaha, R.K., Kaul, D., Kaur, J.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2017
• Subjects: Original contributions
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/137619
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Aberrant promoter hypermethylation of selected apoptotic genes in childhood acute lymphoblastic leukemia among north indian population / M. Nikbakht, A.K. Jha, K. Malekzadeh, M. Askari, S. Mohammadi, R.K. Marwaha, D. Kaul, J. Kaur // Experimental Oncology. — 2017 — Т. 39, № 1. — С. 57-64. — Бібліогр.: 51 назв. — англ.

Promoter hypermethylation mediates gene silencing in many neoplasms. Acute leukemia has been reported to harbor multiple genes aberrantly silenced by hypermethylation. Aim: In present study, we investigated the prevalence of hypermethylation of caspase-8 (CASP8), TMS1 and DAPK genes in correlation w...