2-deoxy-D-glucose enhances dichloroacetate antitumor action against lewis lung carcinoma

• Published in: Experimental Oncology
• Date: 2016
• Main Authors: Pyaskovskaya, O.N., Kolesnik, D.L., Fedorchuk, A.G., Prochorova, I.V., Solyanik, G.I.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2016
• Subjects: Original contributions
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/137717
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: 2-deoxy-D-glucose enhances dichloroacetate antitumor action against lewis lung carcinoma / O.N. Pyaskovskaya, D.L. Kolesnik, A.G. Fedorchuk, I.V. Prochorova, G.I. Solyanik // Experimental Oncology. — 2016 — Т. 38, № 3. — С. 176–180. — Бібліогр.: 27 назв. — англ.

Aerobic glycolysis that supports high proliferation rate and survival of tumor cells in unfavorable conditions is among fundamental features of tumor metabolism. The search for active modulators of energetic metabolism capable of suppressing tumor growth and metastasis could result in higher effecti...