Regulated expression of human beta-defensin-2 leads to altered phenotype and growth patterns of cultured human embryonal kidney cells

• Date: 2006
• Main Authors: Zhuravel, E., Lytvyn, D., Soldatkina, M., Zeleniy, S., Shestakova, T., Pogrebnoy, P.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2006
• Subjects: Original contributions
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/137929
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Regulated expression of human beta-defensin-2 leads to altered phenotype and growth patterns of cultured human embryonal kidney cells / E. Zhuravel, D. Lytvyn, M. Soldatkina, S. Zeleniy, T. Shestakova, P. Pogrebnoy // Experimental Oncology. — 2006. — Т. 28, № 4. — С. 288-292. — Бібліогр.: 21 назв. — англ.

Aim: To create cell line with regulated expression of human beta-defensin-2 (hBD-2) and evaluate the influence of expressed peptide on its phenotypic and growth patterns. Materials and Methods: Using cloning techniques, on the base of human embryonic kidney cells of HEK293T line, stable T-rex HEK-hB...