Effect of 5-azacytidine on mirna expression in human breast cancer cells with different sensitivity to cytostatics

• Published in: Experimental Oncology
• Date: 2016
• Main Authors: Chekhun, V.F., Borikun, T.V., Lukianova, N.Y.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2016
• Subjects: Original contributions
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/137982
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Effect of 5-azacytidine on mirna expression in human breast cancer cells with different sensitivity to cytostatics / V.F. Chekhun, T.V. Borikun, N.Y. Lukianova // Experimental Oncology. — 2016 — Т. 38, № 1. — С. 26–30. — Бібліогр.: 32 назв. — англ.

Aim: To analyze expression of miRNA in human breast cancer cells, sensitive and resistant to cisplatin and doxorubicin, and to explore possible modification of drug sensitivity via treatment of cells with 5-azacytidine (5-aza), a demethylating agent. Materials and Methods: The study was performed on...