Establishment and characterization of new breast and ovarian cancer cell lines as a model for studying cellular plasticity in vitro

• Published in: Experimental Oncology
• Date: 2016
• Main Authors: Bezdieniezhnykh, N., Lykhova, A., Semesiuk, N., Okhrimenko, R., Kudryavets, Yu.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2016
• Subjects: Original contributions
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/138000
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Establishment and characterization of new breast and ovarian cancer cell lines as a model for studying cellular plasticity in vitro / N. Bezdieniezhnykh, A. Lykhova, N. Semesiuk, R. Okhrimenko, Yu. Kudryavets // Experimental Oncology. — 2016 — Т. 38, № 2. — С. 94–10. — Бібліогр.: 19 назв. — англ.

Aim: To compare biological properties of primary tumor cells isolated from malignant effusion of cancer patients with the same cells of permanent lines established during their long-term cultivation in vitro and to assess the impact of phenotypic conversion that was caused by changes in their microe...