Synergistic therapeutic effect of arsenic trioxide and radiotherapy in BALB/C nude mice bearing nasopharyngeal carcinoma xenografts

• Date: 2007
• Main Authors: Xie, L.X., Lin, X.H., Li, D.R., Chen, J.Y., Hong, C.Q., Du, C.W.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2007
• Series: Experimental Oncology
• Subjects: Original contributions
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/138563
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Synergistic therapeutic effect of arsenic trioxide and radiotherapy in BALB/C nude mice bearing nasopharyngeal carcinoma xenografts / L.X. Xie, X.H. Lin, D.R. Li, J.Y. Chen, C.Q. Hong, C.W. Du // Experimental Oncology. — 2007. — Т. 29, № 1. — С. 45-48. — Бібліогр.: 18 назв. — англ.

It has been shown that arsenic trioxide (ATO) induced apoptosis in human nasopharyngeal carcinoma cells and inhibited the growth of nasopharyngeal carcinoma xenografts (NPCX) in nude mice. Aim: The present study was designed to determine whether ATO at the non-toxic dose level could potentiate the t...