Autogeneic RNA-electroporated CD40-ligand activated B-cells from hepatocellular carcinoma patients induce CD8+ T-cell responses ex vivo
Since dendritic cells (DCs) constitute only 0.1–0.5% of human peripheral blood mononuclear cells (PBMCs), and generation of DCs from monocytes or stem cells is difficult and expensive, we choose B-lymphocytes as an alternative, cost-effective source of antigen presenting cells (APC). Aim: To induce...
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| Published in: | Experimental Oncology |
|---|---|
| Date: | 2007 |
| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2007
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| Subjects: | |
| Online Access: | https://nasplib.isofts.kiev.ua/handle/123456789/138573 |
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| Journal Title: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Cite this: | Autogeneic RNA-electroporated CD40-ligand activated B-cells from hepatocellular carcinoma patients induce CD8+ T-cell responses ex vivo / S. Shen, Z. Xu, X. Qian, Y. Ding, L. Yu, B. Liu // Experimental Oncology. — 2007. — Т. 29, № 2. — С. 137-143. — Бібліогр.: 49 назв. — англ. |