Cytotoxic activity of metformin in vitro does not correlate with its antitumor action in vivo

• Published in: Experimental Oncology
• Date: 2017
• Main Authors: Pyaskovskaya, O.N., Kolesnik, D.L., Fedorchuk, A.G., Gorbik, G.V., Solyanik, G.I.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2017
• Subjects: Original contributions
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/138585
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Cytotoxic activity of metformin in vitro does not correlate with its antitumor action in vivo / O.N. Pyaskovskaya, D.L. Kolesnik, A.G. Fedorchuk, G.V. Gorbik, G.I. Solyanik // Experimental Oncology. — 2017 — Т. 39, № 4. — С. 264–268. — Бібліогр.: 22 назв. — англ.

It is known that metformin is a hypoglycemic drug used to treat type II diabetes mellitus. Recently active studies of its antitumor activity in relation to different types of malignant cells are conducted. Aim: To determine the relationship between cytotoxic activity of metformin in vitro and its an...