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Hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies

It is proposed to use the novel paradigm of treating cancer with hyperthermic therapy using multi-walled carbon nanotubes (MWCNT) stimulated with near infrared (NIR) irradiation. Aim: To establish the capacity of MWCNT stimulated with NIR irradiation to destroy Erlich ascitic carcinoma (EAC) cells....

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Published in:Experimental Oncology
Date:2010
Main Authors: Burlaka, A., Lukin, S., Prylutska, S., Remeniak, O., Prylutskyy, Yu., Shuba, M., Maksimenko, S., Ritter, U., Scharff, P.
Format: Article
Language:English
Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2010
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Short communications
Online Access:https://nasplib.isofts.kiev.ua/handle/123456789/138596
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Journal Title:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Cite this:Hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies / A. Burlaka, S. Lukin, S. Prylutska, O. Remeniak, Yu. Prylutskyy, M. Shuba, S. Maksimenko, U. Ritter, P. Scharff // Experimental Oncology. — 2010. — Т. 32, № 1. — С. 48-50. — Бібліогр.: 15 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine
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author Burlaka, A.
Lukin, S.
Prylutska, S.
Remeniak, O.
Prylutskyy, Yu.
Shuba, M.
Maksimenko, S.
Ritter, U.
Scharff, P.
author_facet Burlaka, A.
Lukin, S.
Prylutska, S.
Remeniak, O.
Prylutskyy, Yu.
Shuba, M.
Maksimenko, S.
Ritter, U.
Scharff, P.
citation_txt Hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies / A. Burlaka, S. Lukin, S. Prylutska, O. Remeniak, Yu. Prylutskyy, M. Shuba, S. Maksimenko, U. Ritter, P. Scharff // Experimental Oncology. — 2010. — Т. 32, № 1. — С. 48-50. — Бібліогр.: 15 назв. — англ.
collection DSpace DC
container_title Experimental Oncology
description It is proposed to use the novel paradigm of treating cancer with hyperthermic therapy using multi-walled carbon nanotubes (MWCNT) stimulated with near infrared (NIR) irradiation. Aim: To establish the capacity of MWCNT stimulated with NIR irradiation to destroy Erlich ascitic carcinoma (EAC) cells. Materials and Methods: EAC cells suspension was irradiated with NIR heating lamp with a wavelength of 0.78–1.40 mm and power density of 3.5 W/cm2 over 1.5 min in the presence of MWCNT (0.1 mg/ml). The changes in the temperature of suspension with the NIR exposure time was measured using the differential cooper-constantan thermocouple. The viability of EAC cells was evaluated by trypan blue staining. Results: The death of 95.2% of EAC cells in the presence of MWCNT was observed after 1.5 min of NIR light irradiation: thermal ablation temperature was ~50 °C. Conclusions: It was demonstrated that addition of MWCNT to EAC cell suspension results in the photo-ablative destruction of cells exposed to short time NIR irradiation.
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institution Digital Library of Periodicals of National Academy of Sciences of Ukraine
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language English
last_indexed 2025-12-07T21:10:14Z
publishDate 2010
publisher Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
record_format dspace
spelling Burlaka, A.
Lukin, S.
Prylutska, S.
Remeniak, O.
Prylutskyy, Yu.
Shuba, M.
Maksimenko, S.
Ritter, U.
Scharff, P.
2018-06-19T10:16:42Z
2018-06-19T10:16:42Z
2010
Hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies / A. Burlaka, S. Lukin, S. Prylutska, O. Remeniak, Yu. Prylutskyy, M. Shuba, S. Maksimenko, U. Ritter, P. Scharff // Experimental Oncology. — 2010. — Т. 32, № 1. — С. 48-50. — Бібліогр.: 15 назв. — англ.
1812-9269
https://nasplib.isofts.kiev.ua/handle/123456789/138596
It is proposed to use the novel paradigm of treating cancer with hyperthermic therapy using multi-walled carbon nanotubes (MWCNT) stimulated with near infrared (NIR) irradiation. Aim: To establish the capacity of MWCNT stimulated with NIR irradiation to destroy Erlich ascitic carcinoma (EAC) cells. Materials and Methods: EAC cells suspension was irradiated with NIR heating lamp with a wavelength of 0.78–1.40 mm and power density of 3.5 W/cm2 over 1.5 min in the presence of MWCNT (0.1 mg/ml). The changes in the temperature of suspension with the NIR exposure time was measured using the differential cooper-constantan thermocouple. The viability of EAC cells was evaluated by trypan blue staining. Results: The death of 95.2% of EAC cells in the presence of MWCNT was observed after 1.5 min of NIR light irradiation: thermal ablation temperature was ~50 °C. Conclusions: It was demonstrated that addition of MWCNT to EAC cell suspension results in the photo-ablative destruction of cells exposed to short time NIR irradiation.
This work was partly supported by a German BMBF grant. S. Prylutska is grateful to the DFG for support.
en
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
Experimental Oncology
Short communications
Hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies
Article
published earlier
spellingShingle Hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies
Burlaka, A.
Lukin, S.
Prylutska, S.
Remeniak, O.
Prylutskyy, Yu.
Shuba, M.
Maksimenko, S.
Ritter, U.
Scharff, P.
Short communications
title Hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies
title_full Hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies
title_fullStr Hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies
title_full_unstemmed Hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies
title_short Hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies
title_sort hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies
topic Short communications
topic_facet Short communications
url https://nasplib.isofts.kiev.ua/handle/123456789/138596
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AT prylutskas hyperthermiceffectofmultiwalledcarbonnanotubesstimulatedwithnearinfraredirradiationforanticancertherapyinvitrostudies
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AT scharffp hyperthermiceffectofmultiwalledcarbonnanotubesstimulatedwithnearinfraredirradiationforanticancertherapyinvitrostudies

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