Hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies
It is proposed to use the novel paradigm of treating cancer with hyperthermic therapy using multi-walled carbon nanotubes (MWCNT) stimulated with near infrared (NIR) irradiation. Aim: To establish the capacity of MWCNT stimulated with NIR irradiation to destroy Erlich ascitic carcinoma (EAC) cells....
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| Veröffentlicht in: | Experimental Oncology |
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| Datum: | 2010 |
| Hauptverfasser: | , , , , , , , , |
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| Sprache: | Englisch |
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Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2010
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Zitieren: | Hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies / A. Burlaka, S. Lukin, S. Prylutska, O. Remeniak, Yu. Prylutskyy, M. Shuba, S. Maksimenko, U. Ritter, P. Scharff // Experimental Oncology. — 2010. — Т. 32, № 1. — С. 48-50. — Бібліогр.: 15 назв. — англ. |
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Digital Library of Periodicals of National Academy of Sciences of Ukraine| _version_ | 1862751254187343872 |
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| author | Burlaka, A. Lukin, S. Prylutska, S. Remeniak, O. Prylutskyy, Yu. Shuba, M. Maksimenko, S. Ritter, U. Scharff, P. |
| author_facet | Burlaka, A. Lukin, S. Prylutska, S. Remeniak, O. Prylutskyy, Yu. Shuba, M. Maksimenko, S. Ritter, U. Scharff, P. |
| citation_txt | Hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies / A. Burlaka, S. Lukin, S. Prylutska, O. Remeniak, Yu. Prylutskyy, M. Shuba, S. Maksimenko, U. Ritter, P. Scharff // Experimental Oncology. — 2010. — Т. 32, № 1. — С. 48-50. — Бібліогр.: 15 назв. — англ. |
| collection | DSpace DC |
| container_title | Experimental Oncology |
| description | It is proposed to use the novel paradigm of treating cancer with hyperthermic therapy using multi-walled carbon nanotubes (MWCNT) stimulated with near infrared (NIR) irradiation. Aim: To establish the capacity of MWCNT stimulated with NIR irradiation to destroy Erlich ascitic carcinoma (EAC) cells. Materials and Methods: EAC cells suspension was irradiated with NIR heating lamp with a wavelength of 0.78–1.40 mm and power density of 3.5 W/cm2 over 1.5 min in the presence of MWCNT (0.1 mg/ml). The changes in the temperature of suspension with the NIR exposure time was measured using the differential cooper-constantan thermocouple. The viability of EAC cells was evaluated by trypan blue staining. Results: The death of 95.2% of EAC cells in the presence of MWCNT was observed after 1.5 min of NIR light irradiation: thermal ablation temperature was ~50 °C. Conclusions: It was demonstrated that addition of MWCNT to EAC cell suspension results in the photo-ablative destruction of cells exposed to short time NIR irradiation.
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| first_indexed | 2025-12-07T21:10:14Z |
| format | Article |
| fulltext | |
| id | nasplib_isofts_kiev_ua-123456789-138596 |
| institution | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| issn | 1812-9269 |
| language | English |
| last_indexed | 2025-12-07T21:10:14Z |
| publishDate | 2010 |
| publisher | Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| record_format | dspace |
| spelling | Burlaka, A. Lukin, S. Prylutska, S. Remeniak, O. Prylutskyy, Yu. Shuba, M. Maksimenko, S. Ritter, U. Scharff, P. 2018-06-19T10:16:42Z 2018-06-19T10:16:42Z 2010 Hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies / A. Burlaka, S. Lukin, S. Prylutska, O. Remeniak, Yu. Prylutskyy, M. Shuba, S. Maksimenko, U. Ritter, P. Scharff // Experimental Oncology. — 2010. — Т. 32, № 1. — С. 48-50. — Бібліогр.: 15 назв. — англ. 1812-9269 https://nasplib.isofts.kiev.ua/handle/123456789/138596 It is proposed to use the novel paradigm of treating cancer with hyperthermic therapy using multi-walled carbon nanotubes (MWCNT) stimulated with near infrared (NIR) irradiation. Aim: To establish the capacity of MWCNT stimulated with NIR irradiation to destroy Erlich ascitic carcinoma (EAC) cells. Materials and Methods: EAC cells suspension was irradiated with NIR heating lamp with a wavelength of 0.78–1.40 mm and power density of 3.5 W/cm2 over 1.5 min in the presence of MWCNT (0.1 mg/ml). The changes in the temperature of suspension with the NIR exposure time was measured using the differential cooper-constantan thermocouple. The viability of EAC cells was evaluated by trypan blue staining. Results: The death of 95.2% of EAC cells in the presence of MWCNT was observed after 1.5 min of NIR light irradiation: thermal ablation temperature was ~50 °C. Conclusions: It was demonstrated that addition of MWCNT to EAC cell suspension results in the photo-ablative destruction of cells exposed to short time NIR irradiation. This work was partly supported by a German BMBF grant. S. Prylutska is grateful to the DFG for support. en Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України Experimental Oncology Short communications Hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies Article published earlier |
| spellingShingle | Hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies Burlaka, A. Lukin, S. Prylutska, S. Remeniak, O. Prylutskyy, Yu. Shuba, M. Maksimenko, S. Ritter, U. Scharff, P. Short communications |
| title | Hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies |
| title_full | Hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies |
| title_fullStr | Hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies |
| title_full_unstemmed | Hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies |
| title_short | Hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies |
| title_sort | hyperthermic effect of multi-walled carbon nanotubes stimulated with near infrared irradiation for anticancer therapy: in vitro studies |
| topic | Short communications |
| topic_facet | Short communications |
| url | https://nasplib.isofts.kiev.ua/handle/123456789/138596 |
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