Photolon enhanccement of ultrasound cytotoxicity
Objective: To evaluate the impact of Photolon on cytostatic and cytotoxic effects of therapeutic range ultrasound in C6 glioma cells. Methods: C6 glioma cells in suspension or monolayer cell culture were exposed to ultrasound (880 kHz, 0.2-0.7 W/cm2) in the presence or absence of Photolon at the con...
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| Published in: | Experimental Oncology |
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| Date: | 2011 |
| Main Authors: | , , |
| Format: | Article |
| Language: | English |
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Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2011
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| Online Access: | https://nasplib.isofts.kiev.ua/handle/123456789/138614 |
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| Journal Title: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Cite this: | Photolon enhanccement of ultrasound cytotoxicity / D.A. Tserkovsky, E.N. Alexandrova, Yu.P. Istomin // Experimental Oncology. — 2011. — Т. 33, № 2. — С. 107-109. — Бібліогр.: 21 назв. — англ. |
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Digital Library of Periodicals of National Academy of Sciences of Ukraine| _version_ | 1862632973632798720 |
|---|---|
| author | Tserkovsky, D.A. Alexandrova, E.N. Istomin, Yu.P. |
| author_facet | Tserkovsky, D.A. Alexandrova, E.N. Istomin, Yu.P. |
| citation_txt | Photolon enhanccement of ultrasound cytotoxicity / D.A. Tserkovsky, E.N. Alexandrova, Yu.P. Istomin // Experimental Oncology. — 2011. — Т. 33, № 2. — С. 107-109. — Бібліогр.: 21 назв. — англ. |
| collection | DSpace DC |
| container_title | Experimental Oncology |
| description | Objective: To evaluate the impact of Photolon on cytostatic and cytotoxic effects of therapeutic range ultrasound in C6 glioma cells. Methods: C6 glioma cells in suspension or monolayer cell culture were exposed to ultrasound (880 kHz, 0.2-0.7 W/cm2) in the presence or absence of Photolon at the concentration of 1 µg/ml in the culture medium, and then cell viability was evaluated. Results: Photolon increased the cytotoxic effect of ultrasound by 1.5-2.3-fold but had no effect on its cytostatic activity. Conclusion: Photolon produces a pronounced sonosensitizing effect on glioma C6 cells and is a promising drug for sonodynamic treatment of malignant tumors.
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| first_indexed | 2025-11-30T14:13:09Z |
| format | Article |
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| id | nasplib_isofts_kiev_ua-123456789-138614 |
| institution | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| issn | 1812-9269 |
| language | English |
| last_indexed | 2025-11-30T14:13:09Z |
| publishDate | 2011 |
| publisher | Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| record_format | dspace |
| spelling | Tserkovsky, D.A. Alexandrova, E.N. Istomin, Yu.P. 2018-06-19T10:39:02Z 2018-06-19T10:39:02Z 2011 Photolon enhanccement of ultrasound cytotoxicity / D.A. Tserkovsky, E.N. Alexandrova, Yu.P. Istomin // Experimental Oncology. — 2011. — Т. 33, № 2. — С. 107-109. — Бібліогр.: 21 назв. — англ. 1812-9269 https://nasplib.isofts.kiev.ua/handle/123456789/138614 Objective: To evaluate the impact of Photolon on cytostatic and cytotoxic effects of therapeutic range ultrasound in C6 glioma cells. Methods: C6 glioma cells in suspension or monolayer cell culture were exposed to ultrasound (880 kHz, 0.2-0.7 W/cm2) in the presence or absence of Photolon at the concentration of 1 µg/ml in the culture medium, and then cell viability was evaluated. Results: Photolon increased the cytotoxic effect of ultrasound by 1.5-2.3-fold but had no effect on its cytostatic activity. Conclusion: Photolon produces a pronounced sonosensitizing effect on glioma C6 cells and is a promising drug for sonodynamic treatment of malignant tumors. en Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України Experimental Oncology Short communications Photolon enhanccement of ultrasound cytotoxicity Article published earlier |
| spellingShingle | Photolon enhanccement of ultrasound cytotoxicity Tserkovsky, D.A. Alexandrova, E.N. Istomin, Yu.P. Short communications |
| title | Photolon enhanccement of ultrasound cytotoxicity |
| title_full | Photolon enhanccement of ultrasound cytotoxicity |
| title_fullStr | Photolon enhanccement of ultrasound cytotoxicity |
| title_full_unstemmed | Photolon enhanccement of ultrasound cytotoxicity |
| title_short | Photolon enhanccement of ultrasound cytotoxicity |
| title_sort | photolon enhanccement of ultrasound cytotoxicity |
| topic | Short communications |
| topic_facet | Short communications |
| url | https://nasplib.isofts.kiev.ua/handle/123456789/138614 |
| work_keys_str_mv | AT tserkovskyda photolonenhanccementofultrasoundcytotoxicity AT alexandrovaen photolonenhanccementofultrasoundcytotoxicity AT istominyup photolonenhanccementofultrasoundcytotoxicity |