Analysis of P53, P16INK4A, PRB and cyclin D1 expression and human papillomavirus in primary ovarian serous carcinoma

• Published in: Experimental Oncology
• Date: 2011
• Main Authors: Bilyk, O.O., Pande, N.T., Buchynska, L.G.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2011
• Subjects: Original contributions
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/138650
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Analysis of P53, P16INK4A, PRB and cyclin D1 expression and human papillomavirus in primary ovarian serous carcinomas / O.O. Bilyk, N.T. Pande, L.G. Buchynska // Experimental Oncology. — 2011. — Т. 33, № 3. — С. 150-156. — Бібліогр.: 32 назв. — англ.

Aim: To evaluate the prognostic relevance of key cell cycle regulatory proteins p53, p16INK4a, pRb and Cyclin D1 expression, the presence of high risk HPVs and their association with clinicopathological parameters and the clinical follow up in ovarian cancer patients. Methods: 53 cases of primary ov...