Mobile genetic elements and cancer. From mutations to gene therapy
In the present review, an association between cancer and the activity of the non-LTR retroelements L1, Alu, and SVA, as well as endogenous retroviruses, in the human genome, is analyzed. Data suggesting that transposons have been involved in embryogenesis and malignization processes, are presented....
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| Published in: | Experimental Oncology |
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| Date: | 2011 |
| Main Authors: | , , |
| Format: | Article |
| Language: | English |
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Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2011
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| Online Access: | https://nasplib.isofts.kiev.ua/handle/123456789/138667 |
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| Journal Title: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Cite this: | Mobile genetic elements and cancer. From mutations to gene therapy / I.A. Kozeretska, S.V. Demydov, L.I. Ostapchenko // Experimental Oncology. — 2011. — Т. 33, № 4. — С. 198-205. — Бібліогр.: 114 назв. — англ. |
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Digital Library of Periodicals of National Academy of Sciences of Ukraine| _version_ | 1862661859761455104 |
|---|---|
| author | Kozeretska, I.A. Demydov, S.V. Ostapchenko, L.I. |
| author_facet | Kozeretska, I.A. Demydov, S.V. Ostapchenko, L.I. |
| citation_txt | Mobile genetic elements and cancer. From mutations to gene therapy / I.A. Kozeretska, S.V. Demydov, L.I. Ostapchenko // Experimental Oncology. — 2011. — Т. 33, № 4. — С. 198-205. — Бібліогр.: 114 назв. — англ. |
| collection | DSpace DC |
| container_title | Experimental Oncology |
| description | In the present review, an association between cancer and the activity of the non-LTR retroelements L1, Alu, and SVA, as well as endogenous retroviruses, in the human genome, is analyzed. Data suggesting that transposons have been involved in embryogenesis and malignization processes, are presented. Events that lead to the activation of mobile elements in mammalian somatic cells, as well as the use of mobile elements in genetic screening and cancer gene therapy, are reviewed.
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| first_indexed | 2025-12-02T12:20:59Z |
| format | Article |
| fulltext | |
| id | nasplib_isofts_kiev_ua-123456789-138667 |
| institution | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| issn | 1812-9269 |
| language | English |
| last_indexed | 2025-12-02T12:20:59Z |
| publishDate | 2011 |
| publisher | Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| record_format | dspace |
| spelling | Kozeretska, I.A. Demydov, S.V. Ostapchenko, L.I. 2018-06-19T11:19:50Z 2018-06-19T11:19:50Z 2011 Mobile genetic elements and cancer. From mutations to gene therapy / I.A. Kozeretska, S.V. Demydov, L.I. Ostapchenko // Experimental Oncology. — 2011. — Т. 33, № 4. — С. 198-205. — Бібліогр.: 114 назв. — англ. 1812-9269 https://nasplib.isofts.kiev.ua/handle/123456789/138667 In the present review, an association between cancer and the activity of the non-LTR retroelements L1, Alu, and SVA, as well as endogenous retroviruses, in the human genome, is analyzed. Data suggesting that transposons have been involved in embryogenesis and malignization processes, are presented. Events that lead to the activation of mobile elements in mammalian somatic cells, as well as the use of mobile elements in genetic screening and cancer gene therapy, are reviewed. Authors thank Andrii Rozhok for help in obtaining some papers and English translation. en Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України Experimental Oncology Reviews Mobile genetic elements and cancer. From mutations to gene therapy Article published earlier |
| spellingShingle | Mobile genetic elements and cancer. From mutations to gene therapy Kozeretska, I.A. Demydov, S.V. Ostapchenko, L.I. Reviews |
| title | Mobile genetic elements and cancer. From mutations to gene therapy |
| title_full | Mobile genetic elements and cancer. From mutations to gene therapy |
| title_fullStr | Mobile genetic elements and cancer. From mutations to gene therapy |
| title_full_unstemmed | Mobile genetic elements and cancer. From mutations to gene therapy |
| title_short | Mobile genetic elements and cancer. From mutations to gene therapy |
| title_sort | mobile genetic elements and cancer. from mutations to gene therapy |
| topic | Reviews |
| topic_facet | Reviews |
| url | https://nasplib.isofts.kiev.ua/handle/123456789/138667 |
| work_keys_str_mv | AT kozeretskaia mobilegeneticelementsandcancerfrommutationstogenetherapy AT demydovsv mobilegeneticelementsandcancerfrommutationstogenetherapy AT ostapchenkoli mobilegeneticelementsandcancerfrommutationstogenetherapy |