Mobile genetic elements and cancer. From mutations to gene therapy

In the present review, an association between cancer and the activity of the non-LTR retroelements L1, Alu, and SVA, as well as endogenous retroviruses, in the human genome, is analyzed. Data suggesting that transposons have been involved in embryogenesis and malignization processes, are presented....

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Бібліографічні деталі
Опубліковано в: :Experimental Oncology
Дата:2011
Автори: Kozeretska, I.A., Demydov, S.V., Ostapchenko, L.I.
Формат: Стаття
Мова:English
Опубліковано: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2011
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Онлайн доступ:https://nasplib.isofts.kiev.ua/handle/123456789/138667
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Назва журналу:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Цитувати:Mobile genetic elements and cancer. From mutations to gene therapy / I.A. Kozeretska, S.V. Demydov, L.I. Ostapchenko // Experimental Oncology. — 2011. — Т. 33, № 4. — С. 198-205. — Бібліогр.: 114 назв. — англ.

Репозитарії

Digital Library of Periodicals of National Academy of Sciences of Ukraine
id nasplib_isofts_kiev_ua-123456789-138667
record_format dspace
spelling Kozeretska, I.A.
Demydov, S.V.
Ostapchenko, L.I.
2018-06-19T11:19:50Z
2018-06-19T11:19:50Z
2011
Mobile genetic elements and cancer. From mutations to gene therapy / I.A. Kozeretska, S.V. Demydov, L.I. Ostapchenko // Experimental Oncology. — 2011. — Т. 33, № 4. — С. 198-205. — Бібліогр.: 114 назв. — англ.
1812-9269
https://nasplib.isofts.kiev.ua/handle/123456789/138667
In the present review, an association between cancer and the activity of the non-LTR retroelements L1, Alu, and SVA, as well as endogenous retroviruses, in the human genome, is analyzed. Data suggesting that transposons have been involved in embryogenesis and malignization processes, are presented. Events that lead to the activation of mobile elements in mammalian somatic cells, as well as the use of mobile elements in genetic screening and cancer gene therapy, are reviewed.
Authors thank Andrii Rozhok for help in obtaining some papers and English translation.
en
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
Experimental Oncology
Reviews
Mobile genetic elements and cancer. From mutations to gene therapy
Article
published earlier
institution Digital Library of Periodicals of National Academy of Sciences of Ukraine
collection DSpace DC
title Mobile genetic elements and cancer. From mutations to gene therapy
spellingShingle Mobile genetic elements and cancer. From mutations to gene therapy
Kozeretska, I.A.
Demydov, S.V.
Ostapchenko, L.I.
Reviews
title_short Mobile genetic elements and cancer. From mutations to gene therapy
title_full Mobile genetic elements and cancer. From mutations to gene therapy
title_fullStr Mobile genetic elements and cancer. From mutations to gene therapy
title_full_unstemmed Mobile genetic elements and cancer. From mutations to gene therapy
title_sort mobile genetic elements and cancer. from mutations to gene therapy
author Kozeretska, I.A.
Demydov, S.V.
Ostapchenko, L.I.
author_facet Kozeretska, I.A.
Demydov, S.V.
Ostapchenko, L.I.
topic Reviews
topic_facet Reviews
publishDate 2011
language English
container_title Experimental Oncology
publisher Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
format Article
description In the present review, an association between cancer and the activity of the non-LTR retroelements L1, Alu, and SVA, as well as endogenous retroviruses, in the human genome, is analyzed. Data suggesting that transposons have been involved in embryogenesis and malignization processes, are presented. Events that lead to the activation of mobile elements in mammalian somatic cells, as well as the use of mobile elements in genetic screening and cancer gene therapy, are reviewed.
issn 1812-9269
url https://nasplib.isofts.kiev.ua/handle/123456789/138667
citation_txt Mobile genetic elements and cancer. From mutations to gene therapy / I.A. Kozeretska, S.V. Demydov, L.I. Ostapchenko // Experimental Oncology. — 2011. — Т. 33, № 4. — С. 198-205. — Бібліогр.: 114 назв. — англ.
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AT ostapchenkoli mobilegeneticelementsandcancerfrommutationstogenetherapy
first_indexed 2025-12-02T12:20:59Z
last_indexed 2025-12-02T12:20:59Z
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