Mobile genetic elements and cancer. From mutations to gene therapy

• Published in: Experimental Oncology
• Date: 2011
• Main Authors: Kozeretska, I.A., Demydov, S.V., Ostapchenko, L.I.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2011
• Subjects: Reviews
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/138667
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Mobile genetic elements and cancer. From mutations to gene therapy / I.A. Kozeretska, S.V. Demydov, L.I. Ostapchenko // Experimental Oncology. — 2011. — Т. 33, № 4. — С. 198-205. — Бібліогр.: 114 назв. — англ.

In the present review, an association between cancer and the activity of the non-LTR retroelements L1, Alu, and SVA, as well as endogenous retroviruses, in the human genome, is analyzed. Data suggesting that transposons have been involved in embryogenesis and malignization processes, are presented....