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Ascorbate depletion increases growth and metastasis of melanoma cells in vitamin C deficient mice

Aim: Our main objective was to determine the effect of ascorbate supplementation in mice unable to synthesize ascorbic acid (gulo KO) when challenged with murine B16FO cancer cells. Methods: Gulo KO female mice 36–40 weeks of age were deprived of or maintained on ascorbate in food and water for 4 we...

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Veröffentlicht in:	Experimental Oncology
Datum:	2011
Hauptverfasser:	Cha, J., Roomi, M.W., Ivanov, V., Kalinovsky, T., Niedzwiecki, A., Rath, M.
Format:	Artikel
Sprache:	Englisch
Veröffentlicht:	Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2011
Schlagworte:	Original contributions
Online Zugang:	https://nasplib.isofts.kiev.ua/handle/123456789/138671
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!
Назва журналу:	Digital Library of Periodicals of National Academy of Sciences of Ukraine
Zitieren:	Ascorbate depletion increases growth and metastasis of melanoma cells in vitamin C deficient mice / J. Cha, M.W. Roomi, V. Ivanov, T. Kalinovsky, A. Niedzwiecki, M. Rath // Experimental Oncology. — 2011. — Т. 33, № 4. — С. 226-230. — Бібліогр.: 20 назв. — англ.

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