Regulatory T cells but not NKT I cells are modulated by a single low-dose Cyclophosphamide in a B cell lymphoma tumor-model

• Published in: Experimental Oncology
• Date: 2012
• Main Authors: Rico, M.J., Rozados, V.R., Mainetti, L.E., Zacarias Fluck, M.F., Matar, P., Scharovsky, O.G.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2012
• Subjects: Original contributions
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/138719
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Regulatory T cells but not NKT I cells are modulated by a single low-dose Cyclophosphamide in a B cell lymphoma tumor-model / M.J. Rico, V.R. Rozados, L.E. Mainetti, M.F. Zacarias Fluck, P. Matar, O.G. Scharovsky // Experimental Oncology. — 2012. — Т. 34, № 1. — С. 38-42. — Бібліогр.: 36 назв. — англ.

Aim: Experimental and clinical studies showed that the administration of cyclophosphamide (Cy) in low doses leads to an enhancement of the antitumor immune response. Our objective was to study the modulation, if any, by low dose Cy, of T regulatory (Treg) and natural killer T (NKT) I cells, two cell...