c-FLIP, a master anti-apoptotic regulator

• Published in: Experimental Oncology
• Date: 2012
• Main Author: Safa, A.R.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2012
• Subjects: Reviews
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/138732
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: c-FLIP, a master anti-apoptotic regulator / A.R. Safa // Experimental Oncology. — 2012. — Т. 34, № 3. — С. 176-184. — Бібліогр.: 97 назв. — англ.

Cellular FLICE (FADD-like IL-1β-converting enzyme)-inhibitory protein (c-FLIP) is a master anti-apoptotic regulator and resistance factor that suppresses tumor necrosis factor-α (TNF-α), Fas-L, and TNF-related apoptosis-inducing ligand (TRAIL)-induced apo­pto­sis, as well as apoptosis triggered by c...