Activation of neutrophils in pathological conditions of ischemia and cardiovascular consequences, roles of nitric oxide /no/ and pharmacological ways of regulation

• Published in: Актуальні проблеми транспортної медицини
• Date: 2013
• Main Author: Rutowski Jan Antoni
• Format: Article
• Language: English
• Published: Фізико-хімічний інститут ім. О.В. Богатського НАН України 2013
• Subjects: Гигиена, эпидемиология, экология
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/138733
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Activation of neutrophils in pathological conditions of ischemia and cardiovascular consequences, roles of nitric oxide /no/ and pharmacological ways of regulation / J.A. Rutowski // Актуальні проблеми транспортної медицини. — 2013. — № 1 (31). — С. 50-57. — Бібліогр.: 15 назв. — англ.

Major role in the pathogenesis of the changes development in the heart tissue due to anoxia during myocardial infarction play activated polymorphonuclear leukocytes. Under conditions of hypoxia activated neutrophils are generating oxygen free radicals and releasing the contents of their granules wit...