O₂·- and NO-associated mechanisms of selective action of redox-active cobalt complexes on tumor tissue

• Published in: Experimental Oncology
• Date: 2007
• Main Authors: Ganusevich, I.I., Burlaka, A.P., Sidorik, E.P., Levitin, I.Ya, Sigan, A.L., Osinsky, S.P.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2007
• Subjects: Original contributions
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/138971
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: O₂·- and NO-associated mechanisms of selective action of redox-active cobalt complexes on tumor tissue / I.I. Ganusevich, A.P. Burlaka, E.P. Sidorik, I.Ya. Levitin, A.L. Sigan, S.P. Osinsky // Experimental Oncology. — 2007. — Т. 29, № 3. — С. 203–206. — Бібліогр.: 28 назв. — англ.

Aim: To study the influence of redox-active cobalt(III) complex with tetradentate Schiff base and nicotinamide as an axial ligand on the rate of superoxide radical-anions generation and levels of NO in tumor and normal tissues of Lewis lung carcinoma bearing mice as well as activity of matrix metall...