Bioenergetic status and hypoxia in Lewis lung carcinoma assessed by 31P NMR spectroscopy: correlation with tumor progression

• Published in: Experimental Oncology
• Date: 2007
• Main Authors: Bubnovskaya, L., Mikhailenko, M., Kovelskaya, A., Osinsky, S.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2007
• Subjects: Original contributions
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/138981
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Bioenergetic status and hypoxia in Lewis lung carcinoma assessed by 31P NMR spectroscopy: correlation with tumor progression / L. Bubnovskaya, V. Mikhailenko, A. Kovelskaya, S. Osinsky // Experimental Oncology. — 2007. — Т. 29, № 3. — С. 207-211. — Бібліогр.: 27 назв. — англ.

Aim: Тo evaluate the hypoxia level and some indices of Lewis lung carcinoma energy metabolism by means of 31Р NMR spectroscopy in perchloric acid (PCA) tissue extracts during growth of primary tumor and metastasis. Мaterials and Methods: C57Bl/6 mice-bearing Lewis lung carcinoma were used in this st...