Anticancer therapy and apoptosis imaging

Early response prediction is considered an essential tool to obtain a more customized anticancer treatment because it allows for the identification of patients who will benefit most from a particular therapy and prevents the exposure of those patients to toxic, non-effective regimens. Recent discove...

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Veröffentlicht in:Experimental Oncology
Datum:2012
Hauptverfasser: Yalcin, T.J., Haimovitz-Friedman, A., Verheij, M.
Format: Artikel
Sprache:Englisch
Veröffentlicht: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2012
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Online Zugang:https://nasplib.isofts.kiev.ua/handle/123456789/139046
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Назва журналу:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Zitieren:Anticancer therapy and apoptosis imaging / T.J. Yang, A. Haimovitz-Friedman, M. Verheij // Experimental Oncology. — 2012. — Т. 34, № 3. — С. 269-276. — Бібліогр.: 94 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine
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Zusammenfassung:Early response prediction is considered an essential tool to obtain a more customized anticancer treatment because it allows for the identification of patients who will benefit most from a particular therapy and prevents the exposure of those patients to toxic, non-effective regimens. Recent discoveries of novel markers in functional imaging have created exciting opportunities for in vivo visualization and quantification of cell death. This review will focus on in vivo apoptosis imaging with various radiotracers as predictive tools for tumor response after anticancer therapy. Particular focus will be on annexin V imaging, a technique with the largest clinical experience to date. This article is part of a Special Issue entitled “Apoptosis: Four Decades Later”.
ISSN:1812-9269