In vitro modification of cisplatin cytotoxicity with magnetic fluid

• Published in: Experimental Oncology
• Date: 2013
• Main Authors: Chekhun, V.F., Yurchenko, O.V., Naleskina, L.A., Demash, D.V., Lukianova, N.Yu., Lozovska, Yu.V.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2013
• Subjects: Original contributions
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/139099
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: In vitro modification of cisplatin cytotoxicity with magnetic fluid / V.F. Chekhun, O.V. Yurchenko, L.A. Naleskina, D.V. Demash, N.Yu. Lukianova, Yu.V. Lozovska // Experimental Oncology. — 2013. — Т. 35, № 1. — С. 15-19. — Бібліогр.: 19 назв. — англ.

Aim: To study cytotoxicity of cisplatin conjugated with magnetic fluid (nanocomposite) upon exposure to magnetic field on sensitive and resistant to cisplatin MCF-7 human breast cancer cells. Methods: Cytotoxic activity was evaluated by MTT-test, intracellular iron accumulation was analyzed cytochem...