Immunohistochemical evaluation of p53 expression in lung cancer of patients with paraneoplastic rheumatic syndrome
Aim: To study p53 expression in the tumor tissue of lung cancer (LC) patients with paraneoplastic rheumatic syndrome (PNRS). Materials and Methods: There have been used either biopsy or surgically resected tumor samples of 140 LC patients (83 patients without PNRS, 57 patients with PNRS). For evalua...
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| Veröffentlicht in: | Experimental Oncology |
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| Datum: | 2013 |
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| Format: | Artikel |
| Sprache: | Englisch |
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Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2013
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| Online Zugang: | https://nasplib.isofts.kiev.ua/handle/123456789/139111 |
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Zitieren: | Immunohistochemical evaluation of p53 expression in lung cancer of patients with paraneoplastic rheumatic syndrome / S.A. Lysenko // Experimental Oncology. — 2013. — Т. 35, № 1. — С. 41-44. — Бібліогр.: 26 назв. — англ. |
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Digital Library of Periodicals of National Academy of Sciences of Ukraine| _version_ | 1862735971222552576 |
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| author | Lysenko, S.A. |
| author_facet | Lysenko, S.A. |
| citation_txt | Immunohistochemical evaluation of p53 expression in lung cancer of patients with paraneoplastic rheumatic syndrome / S.A. Lysenko // Experimental Oncology. — 2013. — Т. 35, № 1. — С. 41-44. — Бібліогр.: 26 назв. — англ. |
| collection | DSpace DC |
| container_title | Experimental Oncology |
| description | Aim: To study p53 expression in the tumor tissue of lung cancer (LC) patients with paraneoplastic rheumatic syndrome (PNRS). Materials and Methods: There have been used either biopsy or surgically resected tumor samples of 140 LC patients (83 patients without PNRS, 57 patients with PNRS). For evaluation of p53 expression in LC samples, immunohistochemical analysis was performed. Results: It has been shown that p53 expression in tumor samples from LC patients with PNRS was significantly higher compared to that in LC patients without PNRS. It has been shown that p53 expression is more frequently registered in patients with lung adenocarcinoma with PNRS than in patients with lung adenocarcinoma without this syndrome. Conclusion: The presence of PNRS in LC patients with p53 expression is associated with higher aggressiveness of tumor.
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| first_indexed | 2025-12-07T19:51:42Z |
| format | Article |
| fulltext | |
| id | nasplib_isofts_kiev_ua-123456789-139111 |
| institution | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| issn | 1812-9269 |
| language | English |
| last_indexed | 2025-12-07T19:51:42Z |
| publishDate | 2013 |
| publisher | Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| record_format | dspace |
| spelling | Lysenko, S.A. 2018-06-19T19:13:15Z 2018-06-19T19:13:15Z 2013 Immunohistochemical evaluation of p53 expression in lung cancer of patients with paraneoplastic rheumatic syndrome / S.A. Lysenko // Experimental Oncology. — 2013. — Т. 35, № 1. — С. 41-44. — Бібліогр.: 26 назв. — англ. 1812-9269 https://nasplib.isofts.kiev.ua/handle/123456789/139111 Aim: To study p53 expression in the tumor tissue of lung cancer (LC) patients with paraneoplastic rheumatic syndrome (PNRS). Materials and Methods: There have been used either biopsy or surgically resected tumor samples of 140 LC patients (83 patients without PNRS, 57 patients with PNRS). For evaluation of p53 expression in LC samples, immunohistochemical analysis was performed. Results: It has been shown that p53 expression in tumor samples from LC patients with PNRS was significantly higher compared to that in LC patients without PNRS. It has been shown that p53 expression is more frequently registered in patients with lung adenocarcinoma with PNRS than in patients with lung adenocarcinoma without this syndrome. Conclusion: The presence of PNRS in LC patients with p53 expression is associated with higher aggressiveness of tumor. en Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України Experimental Oncology Original contributions Immunohistochemical evaluation of p53 expression in lung cancer of patients with paraneoplastic rheumatic syndrome Article published earlier |
| spellingShingle | Immunohistochemical evaluation of p53 expression in lung cancer of patients with paraneoplastic rheumatic syndrome Lysenko, S.A. Original contributions |
| title | Immunohistochemical evaluation of p53 expression in lung cancer of patients with paraneoplastic rheumatic syndrome |
| title_full | Immunohistochemical evaluation of p53 expression in lung cancer of patients with paraneoplastic rheumatic syndrome |
| title_fullStr | Immunohistochemical evaluation of p53 expression in lung cancer of patients with paraneoplastic rheumatic syndrome |
| title_full_unstemmed | Immunohistochemical evaluation of p53 expression in lung cancer of patients with paraneoplastic rheumatic syndrome |
| title_short | Immunohistochemical evaluation of p53 expression in lung cancer of patients with paraneoplastic rheumatic syndrome |
| title_sort | immunohistochemical evaluation of p53 expression in lung cancer of patients with paraneoplastic rheumatic syndrome |
| topic | Original contributions |
| topic_facet | Original contributions |
| url | https://nasplib.isofts.kiev.ua/handle/123456789/139111 |
| work_keys_str_mv | AT lysenkosa immunohistochemicalevaluationofp53expressioninlungcancerofpatientswithparaneoplasticrheumaticsyndrome |