Effect of anticancer drugs on production of transforming growth factor and expression of P53 and BCL-2 proteins by MCF-7 and T47D cell lines of human breast carcinoma

• Published in: Experimental Oncology
• Date: 2008
• Main Authors: Stoika, R.S., Yakymovych, I.A., Kashchak, N.I., Boyko, M.M., Korynevska, A.V., Klyuchyvska, O.Yu., Shafranska, G.I., Yakymovych, M.Ya., Zhylchuk, V.Ye., Kudryavets, Yu.Y., Vorontsova, A.L.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2008
• Subjects: Uncategorized
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/139225
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Effect of anticancer drugs on production of transforming growth factor and expression of P53 and BCL-2 proteins by MCF-7 and T47D cell lines of human breast carcinoma / R.S. Stoika, I.A. Yakymovych, N.I. Kashchak, M.M. Boyko, А.V. Korynevska, О.Yu. Klyuchyvska, G.I. Shafranska, M.Ya. Yakymovych, V.Ye. Zhylchuk, Yu.Y. Kudryavets, A.L. Vorontsova // Experimental Oncology. — 2008. — Т. 30, № 1. — С. 35–41. — Бібліогр.: 20 назв. — англ.

Aim: To compare the capability of methotrexate, cisplatin, doxorubicine and vincristine to induce production of the transforming growth factor b1 (TGF- b1) in two cell lines — MCF-7 and T47D — of human breast carcinoma, as well as to study sensitivity of these cells to TGF- b1 and mentioned anticanc...