VEGF-siRNA silencing induces apoptosis, inhibits proliferation and suppresses vasculogenic mimicry in osteosarcoma in vitro

• Published in: Experimental Oncology
• Date: 2008
• ISSN: 1812-9269
• Main Authors: Mei, J., Gao, Y., Zhang, L., Cai, X., Qian, Z., Huang, H., Huang, W.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2008
• Subjects: Uncategorized
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/139228
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: VEGF-siRNA silencing induces apoptosis, inhibits proliferation and suppresses vasculogenic mimicry in osteosarcoma in vitro / J. Mei, Y. Gao, L. Zhang, X. Cai, Z. Qian, H. Huang, W. Huang // Experimental Oncology. — 2008. — Т. 30, № 1. — С. 29–34. — Бібліогр.: 17 назв. — англ.

Aim: To inhibit the gene expression of vascular endothelial growth factor (VEGF) with the RNA interference (RNAi) technique and explore its influence on the apoptosis, proliferation, vasculogenic mimicry of osteosarcoma in vitro. Methods: PSilencer-VEGF plasmid transfected into osteosarcoma cell lin...