Expression of MDR1, LRP, BCRP and BCL-2 genes at diagnosis of childhood ALL: comparison with mrd status after induction therapy

• Published in: Experimental Oncology
• Date: 2008
• Main Authors: Fedasenka, U.U., Shman, T.V., Savitski, V.P., Belevcev, M.V.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2008
• Subjects: Uncategorized
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/139903
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Expression of MDR1, LRP, BCRP and BCL-2 genes at diagnosis of childhood ALL: comparison with mrd status after induction therapy / U.U. Fedasenka, T.V. Shman, V.P. Savitski, M.V. Belevcev // Experimental Oncology. — 2008. — Т. 30, № 3. — С. 248–252. — Бібліогр.: 51 назв. — англ.

To investigate properties of leukemic cells by sorting out children diagnosed with ALL with different response to chemotherapy based on MRD level. Methods: We used a minimal residual disease (MRD) data on day 36 obtained with 3-colour flow cytometry as a reference. In view of MRD results, we used re...