Differential effects of low and high doses of taxol in anaplastic thyroid cancer cells: possible implication of the PIN1 prolyl isomerase

• Published in: Experimental Oncology
• Date: 2008
• Main Authors: Pushkarev, V.M., Starenki, D.V., Saenko, V.A., Pushkarev, V.V., Kovzun, O.I., Tronko, M.D., Popadiuk, I.D., Yamashita, S.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2008
• Subjects: Original contributions
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/139905
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Differential effects of low and high doses of taxol in anaplastic thyroid cancer cells: possible implication of the PIN1 prolyl isomerase / V.M. Pushkarev, D.V. Starenki, V.A. Saenko, V.V. Pushkarev, O.I. Kovzun, M.D. Tronko, I.D. Popadiuk, S. Yamashita // Experimental Oncology. — 2008. — Т. 30, № 3. — С. 190–194. — Бібліогр.: 32 назв. — англ.

To study the molecular mechanisms of dose-dependent effects of an anticancer drug, Taxol, on the cell cycle machinery and apoptosis-related proteins in thyroid anaplastic cancer cell lines ARO and KTC-2. Materials and Methods: Western blot analysis was used for the detection of various proteins and...