Role of postmastectomy radiation therapy after neoadjuvant chemotherapy in locally advanced breast cancer

Neoadjuvant chemotherapy for primary breast cancer is the gold standard in the treatment of locally advanced, inoperable breast cancer, and also based on a large body of evidence has become a standard treatment option for patients with operable disease, who are clear candidates for adjuvant chemothe...

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Veröffentlicht in:Experimental Oncology
Datum:2013
Hauptverfasser: Akyurek, S., Yavas, G
Format: Artikel
Sprache:English
Veröffentlicht: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2013
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Online Zugang:https://nasplib.isofts.kiev.ua/handle/123456789/145237
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Назва журналу:Digital Library of Periodicals of National Academy of Sciences of Ukraine
Zitieren:Role of postmastectomy radiation therapy after neoadjuvant chemotherapy in locally advanced breast cancer / S. Akyurek, G. Yavas // Experimental Oncology. — 2013. — Т. 35, № 4. — С. 267-271. — Бібліогр.: 35 назв. — англ.

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Digital Library of Periodicals of National Academy of Sciences of Ukraine
id nasplib_isofts_kiev_ua-123456789-145237
record_format dspace
spelling Akyurek, S.
Yavas, G
2019-01-19T18:16:33Z
2019-01-19T18:16:33Z
2013
Role of postmastectomy radiation therapy after neoadjuvant chemotherapy in locally advanced breast cancer / S. Akyurek, G. Yavas // Experimental Oncology. — 2013. — Т. 35, № 4. — С. 267-271. — Бібліогр.: 35 назв. — англ.
1812-9269
https://nasplib.isofts.kiev.ua/handle/123456789/145237
Neoadjuvant chemotherapy for primary breast cancer is the gold standard in the treatment of locally advanced, inoperable breast cancer, and also based on a large body of evidence has become a standard treatment option for patients with operable disease, who are clear candidates for adjuvant chemotherapy. There are several advantages of administering neoadjuvant chemotherapy: tumor downstaging, improving the chance of breast conserving surgery, in vivo assessment of tumor sensitivity to the chosen therapeutic regimen, and early control of micro-metastatic disease. However there are substantially less data to aid in determining which patients treated with neo-adjuvant chemotherapy warrant postmastectomy radiotherapy. According to the recent literature, patients who require mastectomy after systemic therapy should receive postmastectomy radiotherapy.
en
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
Experimental Oncology
Special issue on breast cancer
Role of postmastectomy radiation therapy after neoadjuvant chemotherapy in locally advanced breast cancer
Article
published earlier
institution Digital Library of Periodicals of National Academy of Sciences of Ukraine
collection DSpace DC
title Role of postmastectomy radiation therapy after neoadjuvant chemotherapy in locally advanced breast cancer
spellingShingle Role of postmastectomy radiation therapy after neoadjuvant chemotherapy in locally advanced breast cancer
Akyurek, S.
Yavas, G
Special issue on breast cancer
title_short Role of postmastectomy radiation therapy after neoadjuvant chemotherapy in locally advanced breast cancer
title_full Role of postmastectomy radiation therapy after neoadjuvant chemotherapy in locally advanced breast cancer
title_fullStr Role of postmastectomy radiation therapy after neoadjuvant chemotherapy in locally advanced breast cancer
title_full_unstemmed Role of postmastectomy radiation therapy after neoadjuvant chemotherapy in locally advanced breast cancer
title_sort role of postmastectomy radiation therapy after neoadjuvant chemotherapy in locally advanced breast cancer
author Akyurek, S.
Yavas, G
author_facet Akyurek, S.
Yavas, G
topic Special issue on breast cancer
topic_facet Special issue on breast cancer
publishDate 2013
language English
container_title Experimental Oncology
publisher Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
format Article
description Neoadjuvant chemotherapy for primary breast cancer is the gold standard in the treatment of locally advanced, inoperable breast cancer, and also based on a large body of evidence has become a standard treatment option for patients with operable disease, who are clear candidates for adjuvant chemotherapy. There are several advantages of administering neoadjuvant chemotherapy: tumor downstaging, improving the chance of breast conserving surgery, in vivo assessment of tumor sensitivity to the chosen therapeutic regimen, and early control of micro-metastatic disease. However there are substantially less data to aid in determining which patients treated with neo-adjuvant chemotherapy warrant postmastectomy radiotherapy. According to the recent literature, patients who require mastectomy after systemic therapy should receive postmastectomy radiotherapy.
issn 1812-9269
url https://nasplib.isofts.kiev.ua/handle/123456789/145237
citation_txt Role of postmastectomy radiation therapy after neoadjuvant chemotherapy in locally advanced breast cancer / S. Akyurek, G. Yavas // Experimental Oncology. — 2013. — Т. 35, № 4. — С. 267-271. — Бібліогр.: 35 назв. — англ.
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