Serum selenium concentration and antioxidant activity in cervical cancer patients before and after treatment
Aim - in the present study, the effect of chemo and radio therapies on serum trace elements content and antioxidant activity in blood serum of cervical cancer patients was evaluated. Among 104 cervical cancer patients selected for the present study, 54 and 50 patients were treated with chemo- and ra...
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| Опубліковано в: : | Experimental Oncology |
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| Дата: | 2013 |
| Автори: | , , , |
| Формат: | Стаття |
| Мова: | Англійська |
| Опубліковано: |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2013
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| Онлайн доступ: | https://nasplib.isofts.kiev.ua/handle/123456789/145238 |
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Цитувати: | Serum selenium concentration and antioxidant activity in cervical cancer patients before and after treatment / D. Subramanyam, K.C.V. Subbaiah, W. Rajendra, V. Lokanatha // Experimental oncology. — 2013. — Т. 35, № 2. — С. 97-100. — Бібліогр.: 30 назв. — англ. |
Репозитарії
Digital Library of Periodicals of National Academy of Sciences of Ukraine| _version_ | 1862551068295036928 |
|---|---|
| author | Subramanyam D. Subbaiah, K.C.V. Rajendra W. Lokanatha V. |
| author_facet | Subramanyam D. Subbaiah, K.C.V. Rajendra W. Lokanatha V. |
| citation_txt | Serum selenium concentration and antioxidant activity in cervical cancer patients before and after treatment / D. Subramanyam, K.C.V. Subbaiah, W. Rajendra, V. Lokanatha // Experimental oncology. — 2013. — Т. 35, № 2. — С. 97-100. — Бібліогр.: 30 назв. — англ. |
| collection | DSpace DC |
| container_title | Experimental Oncology |
| description | Aim - in the present study, the effect of chemo and radio therapies on serum trace elements content and antioxidant activity in blood serum of cervical cancer patients was evaluated. Among 104 cervical cancer patients selected for the present study, 54 and 50 patients were treated with chemo- and radiotherapy respectively. Plasma Se, Zn, Cu and some enzymatic antioxidants activities were estimated in serum before and after the treatment. The decreased levels of serum trace elements, glutathione peroxidase activity and total antioxidant capacity, and increased malondialdehyde, glutathion reductase was observed in cervical cancer patients when compared to healthy controls. The increased concentration of serum Se, Zn was observed in patients treated with chemotherapy. Simultaneously there was a significant (P << 0,001) increase in glutathione peroxidase and total antioxidant capacity, and significant decrease (P << 0,05) in malondialdehyde and glutathion reductase levels in the serum of patients treated with chemotherapy compared to the patients treated with radiotherapy.
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| first_indexed | 2025-11-25T20:55:02Z |
| format | Article |
| fulltext | |
| id | nasplib_isofts_kiev_ua-123456789-145238 |
| institution | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| issn | 1812-9269 |
| language | English |
| last_indexed | 2025-11-25T20:55:02Z |
| publishDate | 2013 |
| publisher | Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| record_format | dspace |
| spelling | Subramanyam D. Subbaiah, K.C.V. Rajendra W. Lokanatha V. 2019-01-19T18:28:16Z 2019-01-19T18:28:16Z 2013 Serum selenium concentration and antioxidant activity in cervical cancer patients before and after treatment / D. Subramanyam, K.C.V. Subbaiah, W. Rajendra, V. Lokanatha // Experimental oncology. — 2013. — Т. 35, № 2. — С. 97-100. — Бібліогр.: 30 назв. — англ. 1812-9269 https://nasplib.isofts.kiev.ua/handle/123456789/145238 Aim - in the present study, the effect of chemo and radio therapies on serum trace elements content and antioxidant activity in blood serum of cervical cancer patients was evaluated. Among 104 cervical cancer patients selected for the present study, 54 and 50 patients were treated with chemo- and radiotherapy respectively. Plasma Se, Zn, Cu and some enzymatic antioxidants activities were estimated in serum before and after the treatment. The decreased levels of serum trace elements, glutathione peroxidase activity and total antioxidant capacity, and increased malondialdehyde, glutathion reductase was observed in cervical cancer patients when compared to healthy controls. The increased concentration of serum Se, Zn was observed in patients treated with chemotherapy. Simultaneously there was a significant (P << 0,001) increase in glutathione peroxidase and total antioxidant capacity, and significant decrease (P << 0,05) in malondialdehyde and glutathion reductase levels in the serum of patients treated with chemotherapy compared to the patients treated with radiotherapy. The authors are thankful to Dr. D.S. Raju Naidu and Dr. P. Chandra Sekharan for providing cervical cancer samples. The authors also thanks to Institutional Ethical committee (IEC), S.V. Medical College, for providing ethical clearance and UGC-BSR-Non-SAP for providing financial assistance. en Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України Experimental Oncology Original contributions Serum selenium concentration and antioxidant activity in cervical cancer patients before and after treatment Article published earlier |
| spellingShingle | Serum selenium concentration and antioxidant activity in cervical cancer patients before and after treatment Subramanyam D. Subbaiah, K.C.V. Rajendra W. Lokanatha V. Original contributions |
| title | Serum selenium concentration and antioxidant activity in cervical cancer patients before and after treatment |
| title_full | Serum selenium concentration and antioxidant activity in cervical cancer patients before and after treatment |
| title_fullStr | Serum selenium concentration and antioxidant activity in cervical cancer patients before and after treatment |
| title_full_unstemmed | Serum selenium concentration and antioxidant activity in cervical cancer patients before and after treatment |
| title_short | Serum selenium concentration and antioxidant activity in cervical cancer patients before and after treatment |
| title_sort | serum selenium concentration and antioxidant activity in cervical cancer patients before and after treatment |
| topic | Original contributions |
| topic_facet | Original contributions |
| url | https://nasplib.isofts.kiev.ua/handle/123456789/145238 |
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