Role of ABC-cassette transporters (MDR1, MRP1, BCRP) in the development of primary and acquired multiple drug resistance in patients with early and metastatic breast cancer

• Published in: Experimental Oncology
• Date: 2013
• Main Authors: Kovalev, A.A., Tsvetaeva, D.A., Grudinskaja, T.V.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2013
• Subjects: Special issue on breast cancer
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/145262
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Role of ABC-cassette transporters (MDR1, MRP1, BCRP) in the development of primary and acquired multiple drug resistance in patients with early and metastatic breast cancer / A.A. Kovalev, D.A. Tsvetaeva, T.V. Grudinskaja // Experimental Oncology. — 2013. — Т. 35, № 4. — С. 287-290. — Бібліогр.: 9 назв. — англ.

The aim of the research was to study the influence of multiple drug resistance (MDR1), multidrug resistance protein 1 (MRP1) and breast cancer resistance protein (BCRP) proteins expression on the effectiveness of chemotherapy in breast cancer (BC) patients. Patients and Methods: The retrospective an...