Receptor status of tumor as prognostic factor in patients with bilateral breast cancer
Aim: To determine the receptor status of tumors as prognostic factor in development of bilateral breast cancer (BBC) and factor of prognosis of disease. Patients and Methods: 272 cases of BBC during the period from 1995 to 2011 in different oncological institutions of Ukraine have been analyzed. Res...
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| Опубліковано в: : | Experimental Oncology |
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| Дата: | 2013 |
| Автори: | , , |
| Формат: | Стаття |
| Мова: | Англійська |
| Опубліковано: |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2013
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| Онлайн доступ: | https://nasplib.isofts.kiev.ua/handle/123456789/145263 |
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Цитувати: | Receptor status of tumor as prognostic factor in patients with bilateral breast cancer / D.Y. Tsyhyka, Y.S. Hotko, O.T. Devinyak // Experimental Oncology. — 2013. — Т. 35, № 4. — С. 291-294. — Бібліогр.: 11 назв. — англ. |
Репозитарії
Digital Library of Periodicals of National Academy of Sciences of Ukraine| _version_ | 1860255004001042432 |
|---|---|
| author | Tsyhyka, D.Y. Hotko, Y.S. Devinyak, O.T. |
| author_facet | Tsyhyka, D.Y. Hotko, Y.S. Devinyak, O.T. |
| citation_txt | Receptor status of tumor as prognostic factor in patients with bilateral breast cancer / D.Y. Tsyhyka, Y.S. Hotko, O.T. Devinyak // Experimental Oncology. — 2013. — Т. 35, № 4. — С. 291-294. — Бібліогр.: 11 назв. — англ. |
| collection | DSpace DC |
| container_title | Experimental Oncology |
| description | Aim: To determine the receptor status of tumors as prognostic factor in development of bilateral breast cancer (BBC) and factor of prognosis of disease. Patients and Methods: 272 cases of BBC during the period from 1995 to 2011 in different oncological institutions of Ukraine have been analyzed. Results: Patients with metachronous BBC with positive status of hormone receptors (HR) of tumors have significantly better indices of overall and progression-free survival (three-years — 95%, five-years — 72%), than patients with HR-negative status (among them nobody has survived over 5 years). In patients with synchronous BBC, the receptor status of tumors has similar influence on the prognosis of survival. Nevertheless, indices of overall survival (65%) and progression-free survival (66%) in HR-positive patients were lower than that at metachronous BBC (overall survival and progression-free survival — 72%). Conclusions: Synchronous breast cancer has more aggressive clinical course than metachronous one. It was determined significant influence of receptor status of tumors on the overall survival and progression-free survival in patients with BBC.
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| first_indexed | 2025-12-07T18:48:09Z |
| format | Article |
| fulltext |
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| id | nasplib_isofts_kiev_ua-123456789-145263 |
| institution | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| issn | 1812-9269 |
| language | English |
| last_indexed | 2025-12-07T18:48:09Z |
| publishDate | 2013 |
| publisher | Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| record_format | dspace |
| spelling | Tsyhyka, D.Y. Hotko, Y.S. Devinyak, O.T. 2019-01-20T08:21:52Z 2019-01-20T08:21:52Z 2013 Receptor status of tumor as prognostic factor in patients with bilateral breast cancer / D.Y. Tsyhyka, Y.S. Hotko, O.T. Devinyak // Experimental Oncology. — 2013. — Т. 35, № 4. — С. 291-294. — Бібліогр.: 11 назв. — англ. 1812-9269 https://nasplib.isofts.kiev.ua/handle/123456789/145263 Aim: To determine the receptor status of tumors as prognostic factor in development of bilateral breast cancer (BBC) and factor of prognosis of disease. Patients and Methods: 272 cases of BBC during the period from 1995 to 2011 in different oncological institutions of Ukraine have been analyzed. Results: Patients with metachronous BBC with positive status of hormone receptors (HR) of tumors have significantly better indices of overall and progression-free survival (three-years — 95%, five-years — 72%), than patients with HR-negative status (among them nobody has survived over 5 years). In patients with synchronous BBC, the receptor status of tumors has similar influence on the prognosis of survival. Nevertheless, indices of overall survival (65%) and progression-free survival (66%) in HR-positive patients were lower than that at metachronous BBC (overall survival and progression-free survival — 72%). Conclusions: Synchronous breast cancer has more aggressive clinical course than metachronous one. It was determined significant influence of receptor status of tumors on the overall survival and progression-free survival in patients with BBC. en Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України Experimental Oncology Special issue on breast cancer Receptor status of tumor as prognostic factor in patients with bilateral breast cancer Article published earlier |
| spellingShingle | Receptor status of tumor as prognostic factor in patients with bilateral breast cancer Tsyhyka, D.Y. Hotko, Y.S. Devinyak, O.T. Special issue on breast cancer |
| title | Receptor status of tumor as prognostic factor in patients with bilateral breast cancer |
| title_full | Receptor status of tumor as prognostic factor in patients with bilateral breast cancer |
| title_fullStr | Receptor status of tumor as prognostic factor in patients with bilateral breast cancer |
| title_full_unstemmed | Receptor status of tumor as prognostic factor in patients with bilateral breast cancer |
| title_short | Receptor status of tumor as prognostic factor in patients with bilateral breast cancer |
| title_sort | receptor status of tumor as prognostic factor in patients with bilateral breast cancer |
| topic | Special issue on breast cancer |
| topic_facet | Special issue on breast cancer |
| url | https://nasplib.isofts.kiev.ua/handle/123456789/145263 |
| work_keys_str_mv | AT tsyhykady receptorstatusoftumorasprognosticfactorinpatientswithbilateralbreastcancer AT hotkoys receptorstatusoftumorasprognosticfactorinpatientswithbilateralbreastcancer AT devinyakot receptorstatusoftumorasprognosticfactorinpatientswithbilateralbreastcancer |