Receptor status of tumor as prognostic factor in patients with bilateral breast cancer
Aim: To determine the receptor status of tumors as prognostic factor in development of bilateral breast cancer (BBC) and factor of prognosis of disease. Patients and Methods: 272 cases of BBC during the period from 1995 to 2011 in different oncological institutions of Ukraine have been analyzed. Res...
Saved in:
| Published in: | Experimental Oncology |
|---|---|
| Date: | 2013 |
| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2013
|
| Subjects: | |
| Online Access: | https://nasplib.isofts.kiev.ua/handle/123456789/145263 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Journal Title: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Cite this: | Receptor status of tumor as prognostic factor in patients with bilateral breast cancer / D.Y. Tsyhyka, Y.S. Hotko, O.T. Devinyak // Experimental Oncology. — 2013. — Т. 35, № 4. — С. 291-294. — Бібліогр.: 11 назв. — англ. |
Institution
Digital Library of Periodicals of National Academy of Sciences of Ukraine| id |
nasplib_isofts_kiev_ua-123456789-145263 |
|---|---|
| record_format |
dspace |
| spelling |
Tsyhyka, D.Y. Hotko, Y.S. Devinyak, O.T. 2019-01-20T08:21:52Z 2019-01-20T08:21:52Z 2013 Receptor status of tumor as prognostic factor in patients with bilateral breast cancer / D.Y. Tsyhyka, Y.S. Hotko, O.T. Devinyak // Experimental Oncology. — 2013. — Т. 35, № 4. — С. 291-294. — Бібліогр.: 11 назв. — англ. 1812-9269 https://nasplib.isofts.kiev.ua/handle/123456789/145263 Aim: To determine the receptor status of tumors as prognostic factor in development of bilateral breast cancer (BBC) and factor of prognosis of disease. Patients and Methods: 272 cases of BBC during the period from 1995 to 2011 in different oncological institutions of Ukraine have been analyzed. Results: Patients with metachronous BBC with positive status of hormone receptors (HR) of tumors have significantly better indices of overall and progression-free survival (three-years — 95%, five-years — 72%), than patients with HR-negative status (among them nobody has survived over 5 years). In patients with synchronous BBC, the receptor status of tumors has similar influence on the prognosis of survival. Nevertheless, indices of overall survival (65%) and progression-free survival (66%) in HR-positive patients were lower than that at metachronous BBC (overall survival and progression-free survival — 72%). Conclusions: Synchronous breast cancer has more aggressive clinical course than metachronous one. It was determined significant influence of receptor status of tumors on the overall survival and progression-free survival in patients with BBC. en Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України Experimental Oncology Special issue on breast cancer Receptor status of tumor as prognostic factor in patients with bilateral breast cancer Article published earlier |
| institution |
Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| collection |
DSpace DC |
| title |
Receptor status of tumor as prognostic factor in patients with bilateral breast cancer |
| spellingShingle |
Receptor status of tumor as prognostic factor in patients with bilateral breast cancer Tsyhyka, D.Y. Hotko, Y.S. Devinyak, O.T. Special issue on breast cancer |
| title_short |
Receptor status of tumor as prognostic factor in patients with bilateral breast cancer |
| title_full |
Receptor status of tumor as prognostic factor in patients with bilateral breast cancer |
| title_fullStr |
Receptor status of tumor as prognostic factor in patients with bilateral breast cancer |
| title_full_unstemmed |
Receptor status of tumor as prognostic factor in patients with bilateral breast cancer |
| title_sort |
receptor status of tumor as prognostic factor in patients with bilateral breast cancer |
| author |
Tsyhyka, D.Y. Hotko, Y.S. Devinyak, O.T. |
| author_facet |
Tsyhyka, D.Y. Hotko, Y.S. Devinyak, O.T. |
| topic |
Special issue on breast cancer |
| topic_facet |
Special issue on breast cancer |
| publishDate |
2013 |
| language |
English |
| container_title |
Experimental Oncology |
| publisher |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| format |
Article |
| description |
Aim: To determine the receptor status of tumors as prognostic factor in development of bilateral breast cancer (BBC) and factor of prognosis of disease. Patients and Methods: 272 cases of BBC during the period from 1995 to 2011 in different oncological institutions of Ukraine have been analyzed. Results: Patients with metachronous BBC with positive status of hormone receptors (HR) of tumors have significantly better indices of overall and progression-free survival (three-years — 95%, five-years — 72%), than patients with HR-negative status (among them nobody has survived over 5 years). In patients with synchronous BBC, the receptor status of tumors has similar influence on the prognosis of survival. Nevertheless, indices of overall survival (65%) and progression-free survival (66%) in HR-positive patients were lower than that at metachronous BBC (overall survival and progression-free survival — 72%). Conclusions: Synchronous breast cancer has more aggressive clinical course than metachronous one. It was determined significant influence of receptor status of tumors on the overall survival and progression-free survival in patients with BBC.
|
| issn |
1812-9269 |
| url |
https://nasplib.isofts.kiev.ua/handle/123456789/145263 |
| citation_txt |
Receptor status of tumor as prognostic factor in patients with bilateral breast cancer / D.Y. Tsyhyka, Y.S. Hotko, O.T. Devinyak // Experimental Oncology. — 2013. — Т. 35, № 4. — С. 291-294. — Бібліогр.: 11 назв. — англ. |
| work_keys_str_mv |
AT tsyhykady receptorstatusoftumorasprognosticfactorinpatientswithbilateralbreastcancer AT hotkoys receptorstatusoftumorasprognosticfactorinpatientswithbilateralbreastcancer AT devinyakot receptorstatusoftumorasprognosticfactorinpatientswithbilateralbreastcancer |
| first_indexed |
2025-12-07T18:48:09Z |
| last_indexed |
2025-12-07T18:48:09Z |
| _version_ |
1850876404255686656 |