Exogenous nitric oxide potentiate DNA damage and alter DNA repair in cells exposed to ionising radiation

• Published in: Experimental Oncology
• Date: 2013
• Main Authors: Mikhailenko, V.M., Muzalov, I.I.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2013
• Subjects: Arrticles not related to special issue topics
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/145268
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Exogenous nitric oxide potentiate DNA damage and alter DNA repair in cells exposed to ionising radiation / V.M. Mikhailenko, I.I. Muzalov // Experimental Oncology. — 2013. — Т. 35, № 4. — С. 318-324. — Бібліогр.: 43 назв. — англ.

The aim of this study was to investigate impact of exogenous nitric oxide (NO) on generation of different types of DNA damages, their transformation, and specificity of DNA repair in cells treated with ionizing radiation (IR). Methods: levels of single-strand and double-strand breaks assessed in per...