Involvement of human beta-defensin-2 in regulation of malignant potential of cultured human melanoma cells

• Published in: Experimental Oncology
• Date: 2014
• Main Authors: Gerashchenko, O., Zhuravel, E., Skachkova, O., Khranovska, N., Pushkarev, V., Pogrebnoy, P., Soldatkina, M.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2014
• Subjects: Original contributions
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/145313
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Involvement of human beta-defensin-2 in regulation of malignant potential of cultured human melanoma cells / O. Gerashchenko, E. Zhuravel, O. Skachkova, N. Khranovska, V. Pushkarev, P. Pogrebnoy, M. Soldatkina // Experimental Oncology. — 2014. — Т. 36, № 1. — С. 17-23. — Бібліогр.: 35 назв. — англ.

Background and Aim: Human beta-defensin-2 (hBD-2) is an antimicrobial cationic peptide capable to control human carcinoma cell growth via cell cycle regulation. The present study was aimed on determination of hBD-2 influence on the growth patterns and malignant potential of cultured human melanoma c...