Expression of human beta-defensins-1–4 in thyroid cancer cells and new insight on biologic activity of hBD-2 in vitro

• Published in: Experimental Oncology
• Date: 2014
• Main Authors: Zhuravel, O.V., Gerashchenko, O.L., Khetsuriani, M.R., Soldatkina, M.A., Pogrebnoy, P.V.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2014
• Subjects: Original contributions
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/145362
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Expression of human beta-defensins-1–4 in thyroid cancer cells and new insight on biologic activity of hBD-2 in vitro / O.V. Zhuravel, O.L. Gerashchenko, M.R. Khetsuriani, M.A. Soldatkina, P.V. Pogrebnoy // Experimental Oncology. — 2014. — Т. 36, № 3. — С. 174-178. — Бібліогр.: 22 назв. — англ.

The study was aimed on analysis of human beta-defensin-1–4 (hBDs) mRNA expression in cultured thyroid cancer cells and evaluation of effects of recombinant hBD-2 (rec-hBD-2) on growth patterns, migration properties and expression of E-cadherin and vimentin in these cells. Methods: The study was perf...