Leukemic blast cells and controversies in models of hematopoiesis

• Published in: Experimental Oncology
• Date: 2015
• ISSN: 1812-9269
• Main Authors: Gluzman, D.F., Sklyarenko, L.M., Zavelevich, M.P., Koval, S.V., Ivanivskaya, T.S.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2015
• Subjects: Reviews
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/145390
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Leukemic blast cells and controversies in models of hematopoiesis / D.F. Gluzman, L.M. Sklyarenko, M.P. Zavelevich, S.V. Koval, T.S. Ivanivskaya // Experimental Oncology. — 2015. — Т. 37, № 1. — С. С. 2-4. — Бібліогр.: 23 назв. — англ.

Classical and up-to-date models of hematopoietic lineage determination are briefly reviewed with the focus on myeloid-based models challenging the existence of the common progenitor for T cells, B cells and NK cells. The analysis of immunophenotype of leukemic blast cells seems to be a promising app...