Metabolic changes during development of Walker-256 carcinosarcoma resistance to doxorubicin

• Published in: Experimental Oncology
• Date: 2015
• Main Authors: Todor, I.N., Lukianova, N.Yu., Shvets, Yu.V., Lozovska, Yu.V., Chekhun, V.F.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2015
• Subjects: Original contributions
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/145449
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Metabolic changes during development of Walker-256 carcinosarcoma resistance to doxorubicin / I.N. Todor, N.Yu. Lukianova, Yu.V. Shvets, Yu.V. Lozovska, V.F. Chekhun // Experimental Oncology. — 2015. — Т. 37, № 1. — С. 19-22. — Бібліогр.: 19 назв. — англ.

Aim: To study indices of energy metabolism, content of K+ and Mg++ both in peripheral blood and in Walker-256 carcinosarcoma during development of resistance to doxorubicin. Methods: Resistance of Walker-256 carcinosarcoma to doxorubicin has been developed through 12 subsequent transplantations of t...