Prognostic significance of MDM2 gene expression in childhood neuroblastoma

• Published in: Experimental Oncology
• Date: 2015
• Main Authors: Inomistova, M.V., Svergun, N.M., Khranovska, N.M., Skachkova, O.V., Gorbach, O.I., Klymnyuk, G.I.
• Format: Article
• Language: English
• Published: Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України 2015
• Subjects: Original contributions
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/145465
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Prognostic significance of MDM2 gene expression in childhood neuroblastoma / M.V. Inomistova, N.M. Svergun, N.M. Khranovska, O.V. Skachkova, O.I. Gorbach, G.I. Klymnyuk // Experimental Oncology. — 2015. — Т. 37, № 2. — С. 111-115. — Бібліогр.: 15 назв. — англ.

Aim: To investigate the association of MDM2 expression at the mRNA levels in neuroblastoma with clinical features and unfavorable disease factors to determine the possibility of it usage as a prognostic marker of neuroblastoma. Materials and Methods: Total RNA and DNA were extracted from tumor tissu...