Primary testicular lymphoma: a single centre experience
Aim: Primary testicular lymphoma (PTL) is an uncommon and aggressive form of extranodal non-Hodgkin’s lymphoma (NHL). We aimed to analyse the clinicopathological characteristics and outcomes of our PTL cases. Materials and Methods: A review was made of the medical records of 339 NHL patients who wer...
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| Опубліковано в: : | Experimental Oncology |
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| Дата: | 2015 |
| Автори: | , , , |
| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2015
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| Онлайн доступ: | https://nasplib.isofts.kiev.ua/handle/123456789/145536 |
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| Назва журналу: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Цитувати: | Primary testicular lymphoma: a single centre experience / Y. Kemal, F. Teker, G. Demirag, I. Yucel // Experimental Oncology. — 2015. — Т. 37, № 3. — С. 223-226. — Бібліогр.: 27 назв. — англ. |
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Kemal, Y. Teker, F. Demirag, G. Yucel, I. 2019-01-22T19:51:19Z 2019-01-22T19:51:19Z 2015 Primary testicular lymphoma: a single centre experience / Y. Kemal, F. Teker, G. Demirag, I. Yucel // Experimental Oncology. — 2015. — Т. 37, № 3. — С. 223-226. — Бібліогр.: 27 назв. — англ. 1812-9269 https://nasplib.isofts.kiev.ua/handle/123456789/145536 Aim: Primary testicular lymphoma (PTL) is an uncommon and aggressive form of extranodal non-Hodgkin’s lymphoma (NHL). We aimed to analyse the clinicopathological characteristics and outcomes of our PTL cases. Materials and Methods: A review was made of the medical records of 339 NHL patients who were treated in the Medical Oncology Department between January 2005 and December 2013. Results: 8 PTL patients were identified from the 339 NHL patients. The average age of the patients was 67.7 ± 7.9 years (range 53–79 years). The mean follow-up time was 24.8 months (range 7–98 months). Inguinal orchiectomy was performed as a diagnostic and initial therapy and all the patients underwent 4–6 cycles of chemoimmunotherapy consisting of cyclophosphamide, doxorubicin, vincristine and prednisone plus rituximab. 4 of 8 patients received intrathecal prophylactic chemotherapy and 6 of 8 patients continued contralateral testis irradiation. Relapse occured in only 1 patient in central nervous system after 6 months who had not received intrathecal prophylaxis. No contralateral testis relapse was observed. Conclusions: Primary testicular NHL is an uncommon entity and we evaluated 8 patients; with one relapse in central nervous system and no relapse in the contralateral testis. Key Words: primary testicular lymphoma, contralateral scrotal irradiation, intratechal chemotherapy. We thank to Dr. Berkhan Topaktas for his advice on the statistical analyses. en Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України Experimental Oncology Original contributions Primary testicular lymphoma: a single centre experience Article published earlier |
| institution |
Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| collection |
DSpace DC |
| title |
Primary testicular lymphoma: a single centre experience |
| spellingShingle |
Primary testicular lymphoma: a single centre experience Kemal, Y. Teker, F. Demirag, G. Yucel, I. Original contributions |
| title_short |
Primary testicular lymphoma: a single centre experience |
| title_full |
Primary testicular lymphoma: a single centre experience |
| title_fullStr |
Primary testicular lymphoma: a single centre experience |
| title_full_unstemmed |
Primary testicular lymphoma: a single centre experience |
| title_sort |
primary testicular lymphoma: a single centre experience |
| author |
Kemal, Y. Teker, F. Demirag, G. Yucel, I. |
| author_facet |
Kemal, Y. Teker, F. Demirag, G. Yucel, I. |
| topic |
Original contributions |
| topic_facet |
Original contributions |
| publishDate |
2015 |
| language |
English |
| container_title |
Experimental Oncology |
| publisher |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
| format |
Article |
| description |
Aim: Primary testicular lymphoma (PTL) is an uncommon and aggressive form of extranodal non-Hodgkin’s lymphoma (NHL). We aimed to analyse the clinicopathological characteristics and outcomes of our PTL cases. Materials and Methods: A review was made of the medical records of 339 NHL patients who were treated in the Medical Oncology Department between January 2005 and December 2013. Results: 8 PTL patients were identified from the 339 NHL patients. The average age of the patients was 67.7 ± 7.9 years (range 53–79 years). The mean follow-up time was 24.8 months (range 7–98 months). Inguinal orchiectomy was performed as a diagnostic and initial therapy and all the patients underwent 4–6 cycles of chemoimmunotherapy consisting of cyclophosphamide, doxorubicin, vincristine and prednisone plus rituximab. 4 of 8 patients received intrathecal prophylactic chemotherapy and 6 of 8 patients continued contralateral testis irradiation. Relapse occured in only 1 patient in central nervous system after 6 months who had not received intrathecal prophylaxis. No contralateral testis relapse was observed. Conclusions: Primary testicular NHL is an uncommon entity and we evaluated 8 patients; with one relapse in central nervous system and no relapse in the contralateral testis. Key Words: primary testicular lymphoma, contralateral scrotal irradiation, intratechal chemotherapy.
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| issn |
1812-9269 |
| url |
https://nasplib.isofts.kiev.ua/handle/123456789/145536 |
| citation_txt |
Primary testicular lymphoma: a single centre experience / Y. Kemal, F. Teker, G. Demirag, I. Yucel // Experimental Oncology. — 2015. — Т. 37, № 3. — С. 223-226. — Бібліогр.: 27 назв. — англ. |
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AT kemaly primarytesticularlymphomaasinglecentreexperience AT tekerf primarytesticularlymphomaasinglecentreexperience AT demiragg primarytesticularlymphomaasinglecentreexperience AT yuceli primarytesticularlymphomaasinglecentreexperience |
| first_indexed |
2025-12-07T15:54:54Z |
| last_indexed |
2025-12-07T15:54:54Z |
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1850865503915999232 |