Primary testicular lymphoma: a single centre experience
Aim: Primary testicular lymphoma (PTL) is an uncommon and aggressive form of extranodal non-Hodgkin’s lymphoma (NHL). We aimed to analyse the clinicopathological characteristics and outcomes of our PTL cases. Materials and Methods: A review was made of the medical records of 339 NHL patients who wer...
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| Published in: | Experimental Oncology |
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| Date: | 2015 |
| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
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Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2015
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| Online Access: | https://nasplib.isofts.kiev.ua/handle/123456789/145536 |
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| Journal Title: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Cite this: | Primary testicular lymphoma: a single centre experience / Y. Kemal, F. Teker, G. Demirag, I. Yucel // Experimental Oncology. — 2015. — Т. 37, № 3. — С. 223-226. — Бібліогр.: 27 назв. — англ. |
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Digital Library of Periodicals of National Academy of Sciences of Ukraine| _version_ | 1862683060534771712 |
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| author | Kemal, Y. Teker, F. Demirag, G. Yucel, I. |
| author_facet | Kemal, Y. Teker, F. Demirag, G. Yucel, I. |
| citation_txt | Primary testicular lymphoma: a single centre experience / Y. Kemal, F. Teker, G. Demirag, I. Yucel // Experimental Oncology. — 2015. — Т. 37, № 3. — С. 223-226. — Бібліогр.: 27 назв. — англ. |
| collection | DSpace DC |
| container_title | Experimental Oncology |
| description | Aim: Primary testicular lymphoma (PTL) is an uncommon and aggressive form of extranodal non-Hodgkin’s lymphoma (NHL). We aimed to analyse the clinicopathological characteristics and outcomes of our PTL cases. Materials and Methods: A review was made of the medical records of 339 NHL patients who were treated in the Medical Oncology Department between January 2005 and December 2013. Results: 8 PTL patients were identified from the 339 NHL patients. The average age of the patients was 67.7 ± 7.9 years (range 53–79 years). The mean follow-up time was 24.8 months (range 7–98 months). Inguinal orchiectomy was performed as a diagnostic and initial therapy and all the patients underwent 4–6 cycles of chemoimmunotherapy consisting of cyclophosphamide, doxorubicin, vincristine and prednisone plus rituximab. 4 of 8 patients received intrathecal prophylactic chemotherapy and 6 of 8 patients continued contralateral testis irradiation. Relapse occured in only 1 patient in central nervous system after 6 months who had not received intrathecal prophylaxis. No contralateral testis relapse was observed. Conclusions: Primary testicular NHL is an uncommon entity and we evaluated 8 patients; with one relapse in central nervous system and no relapse in the contralateral testis. Key Words: primary testicular lymphoma, contralateral scrotal irradiation, intratechal chemotherapy.
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| first_indexed | 2025-12-07T15:54:54Z |
| format | Article |
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| id | nasplib_isofts_kiev_ua-123456789-145536 |
| institution | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| issn | 1812-9269 |
| language | English |
| last_indexed | 2025-12-07T15:54:54Z |
| publishDate | 2015 |
| publisher | Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України |
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| spelling | Kemal, Y. Teker, F. Demirag, G. Yucel, I. 2019-01-22T19:51:19Z 2019-01-22T19:51:19Z 2015 Primary testicular lymphoma: a single centre experience / Y. Kemal, F. Teker, G. Demirag, I. Yucel // Experimental Oncology. — 2015. — Т. 37, № 3. — С. 223-226. — Бібліогр.: 27 назв. — англ. 1812-9269 https://nasplib.isofts.kiev.ua/handle/123456789/145536 Aim: Primary testicular lymphoma (PTL) is an uncommon and aggressive form of extranodal non-Hodgkin’s lymphoma (NHL). We aimed to analyse the clinicopathological characteristics and outcomes of our PTL cases. Materials and Methods: A review was made of the medical records of 339 NHL patients who were treated in the Medical Oncology Department between January 2005 and December 2013. Results: 8 PTL patients were identified from the 339 NHL patients. The average age of the patients was 67.7 ± 7.9 years (range 53–79 years). The mean follow-up time was 24.8 months (range 7–98 months). Inguinal orchiectomy was performed as a diagnostic and initial therapy and all the patients underwent 4–6 cycles of chemoimmunotherapy consisting of cyclophosphamide, doxorubicin, vincristine and prednisone plus rituximab. 4 of 8 patients received intrathecal prophylactic chemotherapy and 6 of 8 patients continued contralateral testis irradiation. Relapse occured in only 1 patient in central nervous system after 6 months who had not received intrathecal prophylaxis. No contralateral testis relapse was observed. Conclusions: Primary testicular NHL is an uncommon entity and we evaluated 8 patients; with one relapse in central nervous system and no relapse in the contralateral testis. Key Words: primary testicular lymphoma, contralateral scrotal irradiation, intratechal chemotherapy. We thank to Dr. Berkhan Topaktas for his advice on the statistical analyses. en Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України Experimental Oncology Original contributions Primary testicular lymphoma: a single centre experience Article published earlier |
| spellingShingle | Primary testicular lymphoma: a single centre experience Kemal, Y. Teker, F. Demirag, G. Yucel, I. Original contributions |
| title | Primary testicular lymphoma: a single centre experience |
| title_full | Primary testicular lymphoma: a single centre experience |
| title_fullStr | Primary testicular lymphoma: a single centre experience |
| title_full_unstemmed | Primary testicular lymphoma: a single centre experience |
| title_short | Primary testicular lymphoma: a single centre experience |
| title_sort | primary testicular lymphoma: a single centre experience |
| topic | Original contributions |
| topic_facet | Original contributions |
| url | https://nasplib.isofts.kiev.ua/handle/123456789/145536 |
| work_keys_str_mv | AT kemaly primarytesticularlymphomaasinglecentreexperience AT tekerf primarytesticularlymphomaasinglecentreexperience AT demiragg primarytesticularlymphomaasinglecentreexperience AT yuceli primarytesticularlymphomaasinglecentreexperience |