Tumor cell heterogeneity
The paper deals with the analysis of literary data on the tumor cell heterogeneity. Phenotypic, genetic and epigenetic mechanisms of heterogeneity are considered. The heterogeneity of metastasis is considered too. The importance for the biology of populations of tumor cells and the sensitivity of tu...
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| Published in: | Experimental Oncology |
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| Date: | 2013 |
| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
Інститут експериментальної патології, онкології і радіобіології ім. Р.Є. Кавецького НАН України
2013
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| Subjects: | |
| Online Access: | https://nasplib.isofts.kiev.ua/handle/123456789/145708 |
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| Journal Title: | Digital Library of Periodicals of National Academy of Sciences of Ukraine |
| Cite this: | Tumor cell heterogeneity / V.F. Chekhun, S.D. Sherban, Z.D. Savtsova // Experimental Oncology. — 2013. — Т. 35, № 3. — С. 154-162. — Бібліогр.: 80 назв. — англ. |
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Digital Library of Periodicals of National Academy of Sciences of Ukraine| Summary: | The paper deals with the analysis of literary data on the tumor cell heterogeneity. Phenotypic, genetic and epigenetic mechanisms of heterogeneity are considered. The heterogeneity of metastasis is considered too. The importance for the biology of populations of tumor cells and the sensitivity of tumors to therapeutic treatment are discussed. Key Words: primary tumor, metastasis, heterogeneity, malignant phenotype, genetic instability, epigenetic factors.
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| ISSN: | 1812-9269 |