Reversible Inactivation of the Dorsal Raphe Nucleus Increases Morphine-Induced Antinociception in Tolerated but not in Nontolerated Rats

• Published in: Нейрофизиология
• Date: 2015
• Main Authors: Sarihi, A., Heshmatian, B., Pahlevani, P., Komaki, A., Haghparast, A.
• Format: Article
• Language: English
• Published: Інститут фізіології ім. О.О. Богомольця НАН України 2015
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/148190
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Reversible Inactivation of the Dorsal Raphe Nucleus Increases Morphine-Induced Antinociception in Tolerated but not in Nontolerated Rats / A. Sarihi, B. Heshmatian, P. Pahlevani, A. Komaki, A. Haghparast // Нейрофизиология. — 2015. — Т. 47, № 3. — С. 248-254. — Бібліогр.: 42 назв. — англ.

We examined possible effects of the state of the dorsal raphe nucleus (DRN) on morphineinduced antinociception in morphine-tolerated and nontolerated rats. Stereotaxically,
 lidocaine (2%) was applied to the DRN for its reversible inactivation. On the test day, all
 animals received...