Improvement of Regional Cerebral Blood Flow After Stimulation of the Nucl. Fastigius in Cerebral Infarction Patients

• Date: 2015
• Main Authors: Li, Q., Yang, J.
• Format: Article
• Language: English
• Published: Інститут фізіології ім. О.О. Богомольця НАН України 2015
• Series: Нейрофизиология
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/148198
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Improvement of Regional Cerebral Blood Flow after Stimulation of the Nucl. Fastigius in Cerebral Infarction Patients / Q. Li, J. Yang // Нейрофизиология. — 2015. — Т. 47, № 3. — С. 280-283. — Бібліогр.: 10 назв. — англ.

Experimental studies reported that focal stimulation of the nucl. fastigius (fastigial nucleus stimulation, FNS) increases regional cerebral blood flow (rCBF) and ameliorates disorders of cerebral blood circulation. The aim of our study was to examine the effect of FNS on rCBF in cerebral infarction patients and to estimate correlation of the respective effect with prognosis and treatment. The rCBF of 20 cerebral infarction patients was measured before and after FNS using single-photon emission computed tomography (SPECT), and the data were subjected to semiquantitative analysis. Results of the neural ability defect test were used to evaluate prognosis. In the above patients, different levels of decreased rCBF were observed. Focal FNS noticeably ameliorated disorders of circulation in both the infarction area and the corresponding contralateral cerebral area (P < 0.05). The SPECT images showed that the improvement of rCBF was more evident in the central region of the lesion than in the surrounding area. Thus, it was demonstrated that FNS treatment enhances rCBF, which is followed by the improvement of clinical symptoms in cerebral infarction patients.