Central Action of Botulinum Toxin Type A – is it Possible?

• Published in: Нейрофизиология
• Date: 2015
• Main Authors: Galazka, M., Soszynski, D., Dmitruk, K.
• Format: Article
• Language: English
• Published: Інститут фізіології ім. О.О. Богомольця НАН України 2015
• Subjects: Обзоры
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/148213
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Central Action of Botulinum Toxin Type A – is it Possible? / M. Galazka, D. Soszynski, K. Dmitruk // Нейрофизиология. — 2015. — Т. 47, № 4. — С. 380-390. — Бібліогр.: 90 назв. — англ.

Botulinum toxin (BoTx) is a product of gram-positive anaerobic bacteria of the Clostridium genus. At present, seven serotypes (A to G) of BoTx have been identified. Each of them functions as a zinc-dependent endopeptidase that hydrolyzes peptide bonds within soluble N-ethylmaleimide-sensitive fac...