Antioxidant Activity-Mediated Neuroprotective Effects of an Antagonist of AT1 Receptors, Candesartan, Against Cerebral Ischemia and Edema in Rats

• Published in: Нейрофизиология
• Date: 2013
• Main Authors: Panahpour, H., Bohlooli, Sh., Motavallibashi, S.E.
• Format: Article
• Language: English
• Published: Інститут фізіології ім. О.О. Богомольця НАН України 2013
• Online Access: https://nasplib.isofts.kiev.ua/handle/123456789/148233
• Journal Title: Digital Library of Periodicals of National Academy of Sciences of Ukraine
• Cite this: Antioxidant Activity-Mediated Neuroprotective Effects of an Antagonist of AT1 Receptors, Candesartan, Against Cerebral Ischemia and Edema in Rats / H. Panahpour, Sh. Bohlooli, S.E. Motavallibashi // Нейрофизиология. — 2013. — Т. 45, № 5. — С. 469-475. — Бібліогр.: 37 назв. — англ.

We examined the effects of post-ischemic blockade of angiotensinAT1 receptors by candesartan on cerebral infarction and formation of edema. Male Sprague–Dawley rats were divided into three groups, sham, control ischemic, and candesartan-treated (0.3 mg/kg) ischemic. Transient focal cerebral ische...